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- Table of Contents
Eotaxin Antibodies
AND CCL11 ELISA kits, Eotaxin Proteins
Many biological assays use antibodies to detect Eotaxin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Eotaxin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Eotaxin antibodies...
Designing a Western blot for Eotaxin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CCL11 Western Blot GuideCCL11 Infographic by Boster Bio
All CCL11 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0329
96 wells/kit, with removable strips.
Cat # EK0329
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0330
96 wells/kit, with removable strips.
Cat # EK0330
96 wells/kit, with removable strips.
Anti-Eotaxin/CCL11 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # PB9569
100 μg/vial
Cat # PB9569
100 μg/vial
Rat Eotaxin ELISA Kit PicoKine®
2 Citations
Rat
ELISA
$499
Cat # EK1435
96 wells/kit, with removable strips.
Cat # EK1435
96 wells/kit, with removable strips.
CCL11 Overview
Facts about Eotaxin.
Eotaxin (CCL11)
In reaction to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL11 |
| Uniprot: | P51671 |
| Entrez: | 6356 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
C-C motif chemokine 11; CCL11; chemokine (C-C motif) ligand 11; Eosinophil chemotactic protein; Eotaxin; eotaxin-1; MGC22554; SCYA11Small-inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
Molecular Weight
Mass (kDA):
10.732 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (34285742..34288334) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Asthma
- Eosinophilia
- Cholangiocarcinoma
- Allergy
- Tissue Adhesions
- Bronchial Hyperreactivity
- Pneumonia
- Allergic Asthma
- Pulmonary Eosinophilia
- Dermatitis
- Rhinorrhea
- Dermatitis, Atopic
Interacting Proteins
- CCL27
- CCL28
- CCL5
- CCR3
- CXCL10
- CXCL12
- DPP4
- PF4
Pathways
- Pathogenesis
- Chemotaxis
- Secretion
- Eosinophil Migration
- Inflammatory Response
- Eosinophil Chemotaxis
- Immune Response
- Sensitization
- Cell Adhesion
- Cell Migration
- Cytokine Production
- Chemokine Production
- Eosinophil Activation
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL11
bosterbio.com/bosterbio-gene-info-cards/CCL11
References
PMID: 8597956 by Garcia-Zepeda E.A., et al. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia.
PMID: 8609214 by Ponath P.D., et al. Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.
9 Publications of Boster Eotaxin Antibodies & ELISA Kits
- PubMed ID: 10.3892/etm.2020.9078, IL‑37 relieves allergic inflammation by inhibiting the CCL11 signaling pathway...
- PubMed ID: 10.1111/coa.12392, Comorbidity has no impact on eosinophil inflammation in the upper airways or on ...
- PubMed ID: 10.1016/j.phymed.2018.12.043, JAX2, an ethanol extract of Hyssopus cuspidatus Boriss, can prevent bronchial as...
- PubMed ID: 10.1016/j.omto.2021.07.014, Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eli...
- PubMed ID: 10.1016/j.jid.2018.10.048, Increased Type 2 Innate Lymphoid Cells in Patients with Drug Reaction with Eosi...
- PubMed ID: 10.1016/j.intimp.2016.12.011, Catalpol alleviates ovalbumin-induced asthma in mice: Reduced eosinophil infiltr...
- PubMed ID: 31505422, Ge Y,Cheng R,Sun S,Zhang S,Li L,Jiang J,Yang C,Xuan X,Chen J.Fangxiao Formula al...
- PubMed ID: 28100959, Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of a...
- PubMed ID: 23506991, Li L, Yu Ch, Ying Hz, Yu Jm. J Ethnopharmacol. 2013 May 2;147(1):238-44. Doi: 10...
*More publications can be found for each product on its corresponding product page