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- Table of Contents
CDC25C Antibodies
AND CDC25C ELISA kits, CDC25C Proteins
Many biological assays use antibodies to detect CDC25C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC25C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC25C antibodies...
Designing a Western blot for CDC25C? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDC25C Western Blot GuideCDC25C Infographic by Boster Bio
All CDC25C Products
Product
Figures
Specificity
Applications
Price
Anti-Cdc25C Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PB9756
100 μg/vial
Cat # PB9756
100 μg/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01343
100 μl
Cat # M01343
100 μl
Human
ELISA, IF, IHC, WB
$380
Cat # M01343-1
100ul
Cat # M01343-1
100ul
Human, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01343-3
20μL, 40μL, 100μL, 200μL
Cat # M01343-3
20μL, 40μL, 100μL, 200μL
Human
ELISA
$540
Cat # EKC2148
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2148
1 kit, containing two 96-well plates and all necessary reagents
CDC25C Overview
Facts about M-phase inducer phosphatase 3.
M-phase inducer phosphatase 3 (CDC25C)
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.
When phosphorylated, highly effective in activating G2 cells to prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC25C |
| Uniprot: | P30307 |
| Entrez: | 995 |
Family
| Belongs to: |
|---|
| MPI phosphatase family |
Alternative Names
CDC 25; CDC25; CDC25C; cell division cycle 25 homolog C (S. cerevisiae); cell division cycle 25 homolog C (S. pombe); cell division cycle 25C; Dual specificity phosphatase Cdc25C; EC 3.1.3.48; mitosis inducer CDC25; M-phase inducer phosphatase 3; phosphotyrosine phosphatase
Molecular Weight
Mass (kDA):
53.365 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.2 |
| Sequence: | 5; NC_000005.10 (138285265..138338355, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Malignant Neoplasm Of Prostate
- Cell Transformation, Neoplastic
- Malignant Tumor Of Colon
- Leukemia
- Prostatic Neoplasms
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Liver Carcinoma
Interacting Proteins
- CDK1
- CHEK1
- LZTS1
- PLK1
- YWHAB
Pathways
- Cell Cycle
- Cell Cycle Arrest
- Mitosis
- Cell Growth
- Cell Proliferation
- Cell Death
- Cell Division
- S Phase
- Localization
- M Phase
- Induction Of Apoptosis
- Dna Damage Checkpoint
- Cell Cycle Checkpoint
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Ubiquitination
- Methylation
- Reduction
- Acetylation
- Demethylation
Research Areas
- Cell Cycle and Replication
- Phospho-Specific
- Protein Phosphatase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC25C
bosterbio.com/bosterbio-gene-info-cards/CDC25C
References
PMID: 2195549 by Sadhu K., et al. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2.
PMID: 11078813 by Bureik M., et al. An additional transcript of the cdc25C gene from A431 cells encodes a functional protein.
2 Publications of Boster CDC25C Antibodies & ELISA Kits
- PubMed ID: 29805667, Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeti...
- PubMed ID: 25176258, Ling H, Lu Lf, He J, Xiao Gh, Jiang H, Su Q. Oncol Rep. 2014 Nov;32(5):2274-82. ...
*More publications can be found for each product on its corresponding product page