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- Table of Contents
CSF3R Antibodies
AND CSF3R ELISA kits, CSF3R Proteins
Many biological assays use antibodies to detect CSF3R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CSF3R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CSF3R antibodies...
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CSF3R Infographic by Boster Bio
All CSF3R Products
Product
Figures
Specificity
Applications
Price
Human CSF3R/G-CSF R ELISA Kit PicoKine®
1 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0766
96 wells/kit, with removable strips.
Cat # EK0766
96 wells/kit, with removable strips.
Human
Flow Cytometry, WB
$370
Cat # M00281
100 μl
Cat # M00281
100 μl
Human
Cell Culture
$77
Cat # PROTQ99062-3
5ug,20ug,100ug
Cat # PROTQ99062-3
5ug,20ug,100ug
Cynomolgus monkey, Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00281-1
100 μg
Cat # M00281-1
100 μg
CSF3R Overview
Facts about Granulocyte colony-stimulating factor receptor.
Granulocyte colony-stimulating factor receptor (CSF3R)
Receptor for granulocyte colony-stimulating variable (CSF3), essential for granulocytic maturation. Plays a vital role in the proliferation, differientation and survival of cells across the neutrophilic lineage.
Moreover it can function in some adhesion or recognition events at the cell surface. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CSF3R |
| Uniprot: | Q99062 |
| Entrez: | 1441 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
CD114 antigen; CD114; colony stimulating factor 3 receptor (granulocyte); CSF3R; Csfgr; G-CSF R; G-CSF receptor; GCSFR; G-CSFR; GCSFRG-CSF-R; granulocyte colony-stimulating factor receptor
Molecular Weight
Mass (kDA):
92.156 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.3 |
| Sequence: | 1; NC_000001.11 (36466043..36483314, complement) |
Tissue Specificity
One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
Subcellular Localizations
[Isoform 2]: Secreted.; Cell membrane; Single-pass type I membrane protein.
Diseases
- Severe Congenital Neutropenia
- Leukemia
- Leukemia, Myelocytic, Acute
- Dysmyelopoietic Syndromes
- Myeloid Leukemia
- Malignant Neoplasms
- Leukemogenesis
- Pancytopenia
- Inflammation
- Malignant Paraganglionic Neoplasm
- Growth Arrest
- Cell Transformation, Neoplastic
Interacting Proteins
- STAT3
- UBC
Pathways
- Cell Development
- Dna Methylation
- Methylation
- Cell Cycle
- Pathogenesis
- Cell Adhesion
- Granulocyte Differentiation
- Cell Activation
- Neutrophil Differentiation
- Hypersensitivity
- Menopause
- Endocytosis
- Localization
PTMs
- Phosphorylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CSF3R
bosterbio.com/bosterbio-gene-info-cards/CSF3R
References
PMID: 2147944 by Larsen A., et al. Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
PMID: 1701053 by Fukunaga R., et al. Three different mRNAs encoding human granulocyte colony-stimulating factor receptor.