C-X-C motif chemokine 3 (CXCL3)

Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils.

May play a role in inflammation and apply its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.