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- Table of Contents
Facts about Gastrin-releasing peptide receptor.
Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but doesn't play a role in the perception of pain.
Human | |
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Gene Name: | GRPR |
Uniprot: | P30550 |
Entrez: | 2925 |
Belongs to: |
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G-protein coupled receptor 1 family |
Gastrin-releasing Peptide R; gastrin-releasing peptide receptor; Gastrinreleasing PeptideR; Gastrin-releasing PeptideR; GRP-preferring bombesin receptor; GRPR; GRP-R
Mass (kDA):
43.199 kDA
Human | |
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Location: | Xp22.2 |
Sequence: | X; NC_000023.11 (16123565..16153518) |
Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.
Cell membrane; Multi-pass membrane protein.
PMID: 1655761 by Corjay M.H., et al. Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells.
PMID: 11245983 by Xiao D., et al. The human gastrin-releasing peptide receptor gene structure, its tissue expression and promoter.