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CYP11B1 Antibodies
AND CYP11B1 ELISA kits, CYP11B1 Proteins
Many biological assays use antibodies to detect CYP11B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP11B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP11B1 antibodies...
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CYP11B1 Infographic by Boster Bio
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CYP11B1 Overview
Facts about Cytochrome P450 11B1, mitochondrial.
Cytochrome P450 11B1, mitochondrial (CYP11B1)
Has steroid 11-beta-hydroxylase action. Besides this action, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP11B1 |
| Uniprot: | P15538 |
| Entrez: | 1584 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
CPN1; CYPXIB1; cytochrome P450 11B1, mitochondrial; cytochrome p450 XIB1; cytochrome P450, family 11, subfamily B, polypeptide 1; cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1; Cytochrome P450C11; Cytochrome P-450c11; EC 1.14.15; EC 1.14.15.4; FHICYP11B; FLJ36771; P450C11DKFZp686B05283; S11BH; Steroid 11-beta-hydroxylase; steroid 11-beta-monooxygenase
Molecular Weight
Mass (kDA):
57.573 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q24.3 |
| Sequence: | 8; NC_000008.11 (142872357..142879825, complement) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein.
Diseases
- Hypertensive Disease
- Hyperplasia
- Congenital Adrenal Hyperplasia
- Adrenal Hyperplasia
- Hyperaldosteronism
- Conn Syndrome
- Adenoma
- Neoplasms
- Tumors Of Adrenal Cortex
- Chronic Active Hepatitis
- 11-beta-hydroxylase Deficiency
- Heart Failure
- Essential Hypertension
Pathways
- Secretion
- Aldosterone Secretion
- Excretion
- Cortisol Secretion
- Gene Conversion
- Localization
- Transport
- Pathogenesis
- Electron Transport
- Water Homeostasis
- Cell Proliferation
- Reverse Transcription
- Cholesterol Transport
PTMs
- Hydroxylation
- Cleavage
- Phosphorylation
- Reduction
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP11B1
bosterbio.com/bosterbio-gene-info-cards/CYP11B1
References
PMID: 2592361 by Mornet E., et al. Characterization of two genes encoding human steroid 11 beta- hydroxylase (P-450(11) beta).
PMID: 2401360 by Kawamoto T., et al. Cloning of cDNA and genomic DNA for human cytochrome P-45011 beta.