Cytochrome P450 2A7 Antibodies

AND CYP2A7 ELISA kits, Cytochrome P450 2A7 Proteins

Many biological assays use antibodies to detect Cytochrome P450 2A7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 2A7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 2A7 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 2A7 by testing them on tissues known to express CYP2A7 positively and negatively. Browse below to find the CYP2A7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP2A7 Infographic by Boster Bio

All CYP2A7 Products

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Anti-Cytochrome P450 2A7 CYP2A7 Antibody

6 Q&As

Western Blot analysis of 22RV1 cells using CYP2A7 Polyclonal Antibody diluted at 1:2000

Human

ELISA, IF, IHC, WB

$399
Cat # A10507
100μl

Anti-Cytochrome P450 2A7 CYP2A7 Antibody

Western blot (WB) analysis of CYP2A7 polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Lane3:PC12 cell lysate

Human, Mouse, Rat

IHC, ICC, WB

$405
Cat # A10507-1
100ul

CYP2A7 (NM_000764) Human Recombinant Protein

Coomassie blue staining of purified CYP2A7 protein

$1249
Cat # PROTP20853
20 µg

CYP2A7 Overview

Facts about Cytochrome P450 2A7.

CYP2A7 3D structure. Source: alphafold

Cytochrome P450 2A7 (CYP2A7)

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.

It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. .

Gene Information

Human
Gene Name:	CYP2A7
Uniprot:	P20853
Entrez:	1549

Family

Belongs to:

cytochrome P450 family

Alternative Names

CPA7; CPAD; CYP2A; CYPIIA7; cytochrome P450 2A7; Cytochrome P450 IIA4; cytochrome P450, family 2, subfamily A, polypeptide 7; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7; EC 1.14.14.1; P450-IIA4

Molecular Weight

Mass (kDA):
56.425 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (40875439..40885951, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Lung
Neoplasms
Liver Carcinoma
Liver Neoplasms
Autoimmunity
Cell Transformation, Neoplastic
Tobacco Dependence Syndrome
Hepatitis
Malignant Neoplasm Of Breast
Hepatitis, Autoimmune
Hepatitis C
Malignant Neoplasm Of Liver

Acute Lymphocytic Leukemia
Carcinoma
Invasive Ductal Breast Carcinoma
Nicotine Dependence
Autoimmune Reaction
Myeloid Leukemia
Leukemia

Pathways

Gene Conversion
Dna Replication
Reverse Transcription
Dna Amplification
Translation
Cell Cycle
Mrna Stabilization
Cell Growth

Pathogenesis
Cell Recognition
Excretion

PTMs

Hydroxylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP2A7

References

PMID: 2322567 by Yamano S., et al. The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes.

PMID: 7668294 by Fernandez-Salguero P., et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.