Beta-defensin 1 Antibodies

AND DEFB1 ELISA kits, Beta-defensin 1 Proteins

Many biological assays use antibodies to detect Beta-defensin 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Beta-defensin 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Beta-defensin 1 antibodies...

We validate the specificity of these antibodies to Beta-defensin 1 by testing them on tissues known to express DEFB1 positively and negatively. Browse below to find the DEFB1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DEFB1 Infographic by Boster Bio

All DEFB1 Products

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Anti-beta Defensin 1/DEFB1 Antibody Picoband®

1 Citations 1 Q&As

Anti-beta Defensin 1 antibody, PA1450, IHC(P)IHC(P): Lung Cancer Tissue

Anti-beta Defensin 1 antibody, PA1450,Western blottingAll lanes: Anti Defensin 1 (PA1450) at 0

Human

IHC, WB

$370
Cat # PA1450
100 μg/vial

Anti-Beta-defensin 1 DEFB1 Antibody

Western blot (WB) analysis of DEFB1 polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Mouse liver tissue lysate
Lane3:Rat heart tissue lysate

Human, Mouse, Rat

$405
Cat # A02551
100ul

Anti-beta Defensin 1 Rabbit Monoclonal Antibody

Human

$370
Cat # M02551
100 μl/vial

DEFB1 Overview

Facts about Beta-defensin 1.

DEFB1 3D structure. Source: alphafold

Beta-defensin 1 (DEFB1)

Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6.

Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent method. Binds to CCR6 and activates Ca2+ mobilization from the sperm which is very important to its motility (PubMed:25122636).

Gene Information

Human
Gene Name:	DEFB1
Uniprot:	P60022
Entrez:	1672

Family

Belongs to:

beta-defensin family

Alternative Names

Beta-defensin 1

Molecular Weight

Mass (kDA):
7.42 kDA

Genomic Context


Human

Location:	8p23.1
Sequence:	8; NC_000008.11 (6870592..6877936, complement)

Tissue Specificity

Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level).

Subcellular Localizations

Secreted. Membrane. Associates with tumor cell membrane-derived microvesicles (PubMed:23938203).

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DEFB1

References

PMID: 9268634 by Liu L., et al. The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.

PMID: 9070620 by McCray P.B. Jr., et al. Human airway epithelia express a beta-defensin.

1 Publications of Boster Beta-defensin 1 Antibodies & ELISA Kits

PubMed ID: 10.5935/0004-2749.20170068, An investigation of human beta-defensins and cathelicidin expression in patients...

*More publications can be found for each product on its corresponding product page