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- Table of Contents
Facts about Beta-defensin 4A.
Can bind to both mouse and human CCR6 and induce chemotactic action of CCR6-expressing cells (PubMed:20068036). .
| Human | |
|---|---|
| Gene Name: | DEFB4A |
| Uniprot: | O15263 |
| Entrez: | 1673 |

| Belongs to: |
|---|
| beta-defensin family |

BD-2; betaDefensin 2; beta-Defensin 2; DEFB2; DEFB-2; DEFB2DEFB102; DEFB4A; DEFB4B; DEFB4beta-defensin 4A; Defensin, beta 2Skin-antimicrobial peptide 1; defensin, beta 4; defensin, beta 4A; HBD-2; SAP-1; SAP1BD-2
Mass (kDA):
7.038 kDA

| Human | |
|---|---|
| Location: | 8p23.1 |
| Sequence: | 8; NC_000008.11 (7894677..7896716) |
Expressed in the skin and respiratory tract.
Secreted.




PMID: 9202117 by Harder J., et al. A peptide antibiotic from human skin.
PMID: 9831658 by Liu L., et al. Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation.