Disrupted in schizophrenia 1 protein (DISC1)

Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B action and CTNNB1 abundance.

Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the speed of the process of toddlers integration during adult neurogenesis, such as neuron placement, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A.