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- Table of Contents
Protein Dok-7 Antibodies
AND Dok7 ELISA kits, Protein Dok-7 Proteins
Many biological assays use antibodies to detect Protein Dok-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Dok-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Dok-7 antibodies...
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Dok7 Infographic by Boster Bio
All Dok7 Products
Product
Figures
Specificity
Applications
Price
Anti-DOK7 Antibody Picoband®
1 Citations 3 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A05165-1
100 μg/vial
Cat # A05165-1
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1841
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1841
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
Flow Cytometry, IF, IHC, WB
$523
Cat # M05165
100 µl
Cat # M05165
100 µl
Dok7 Overview
Facts about Protein Dok-7.
Protein Dok-7 (Dok7)
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes.
Induces autophosphorylation of MUSK. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Dok7 |
| Uniprot: | Q18PE0 |
| Entrez: | 231134 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C4orf25; C4orf25chromosome 4 open reading frame 25; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; FLJ33718; FLJ39137; FLJ90556; protein Dok-7
Molecular Weight
Mass (kDA):
53.177 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 5|5 B2 |
| Sequence: | 5; |
Diseases
- Myasthenic Syndromes, Congenital
- Weakness
- Myasthenias
- Muscle Weakness
- Myasthenia Gravis
- Autoimmune Reaction
- Autoimmune Diseases
- Blepharoptosis
- Muscular Dystrophies, Limb-girdle
- Myopathy
- Malignant Neoplasms
Pathways
- Localization
- Pathogenesis
- Muscle Contraction
- Dna Hypermethylation
- Aging
- Dna Methylation
- Synaptic Transmission
- Muscle Atrophy
- Nuclear Export
- Methylation
- Regeneration
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dok7
bosterbio.com/bosterbio-gene-info-cards/Dok7
References
PMID: 16794080 by Okada K., et al. The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.
PMID: 20603078 by Bergamin E., et al. The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.
1 Publications of Boster Protein Dok-7 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.biopha.2018.06.156, Repression of Dok7 expression mediated by DNMT1 promotes glioma cells proliferat...
*More publications can be found for each product on its corresponding product page