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Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 important interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines as well as the formation of excitatory synapses.
|protein kinase superfamily|
|Sequence:||3; NC_000003.12 (184561785..184582408)|
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite.