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- Table of Contents
Facts about Endoplasmic reticulum aminopeptidase 1.
Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides using a hydrophobic C-terminus, while it has weak activity toward peptides with billed C-terminus.
Human | |
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Gene Name: | ERAP1 |
Uniprot: | Q9NZ08 |
Entrez: | 51752 |
Belongs to: |
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peptidase M1 family |
Adipocyte-derived leucine aminopeptidase; A-LAP; A-LAPALAP; Aminopeptidase PILS; ARTS1; ARTS1aminopeptidase regulator of TNFR1 shedding; ARTS-1PILSAP; EC 3.4.11; EC 3.4.11.-; EC 3.4.11.1; endoplasmic reticulum aminopeptidase 1; endoplasmic reticulum aminopeptidase associated with antigen processing; ERAAP1; ERAP1; KIAA0525APPILS; PILS-AP; PILS-APERAAP; Puromycin-insensitive leucyl-specific aminopeptidase; Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
Mass (kDA):
107.235 kDA
Human | |
---|---|
Location: | 5q15 |
Sequence: | 5; NC_000005.10 (96760273..96935983, complement) |
Ubiquitous.
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
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If you are interested in the history of Steven Boster, you have come to the right place. Public records include current and previous addresses, phone numbers, email addresses and known relatives. You can filter the public records by age and state to find out even more information about him. The free public records search tool can be used to quickly check the background of Steve Boster.
Steve Boster, a Joliet, IL native, died in Madison, WI on June 6, 2022. He was a veteran of the U.S. Army and a member of Concordia Hall in Staunton, VA. Boster is survived by two daughters, Natosha Peck and Crystal Boster, 6 Grandchildren, and 4 Brothers, Jack Boster, Sandra Blanton, and Lisa Milton. Boster is survived not only by his family but also by many nieces and nephews.
PMID: 10220586 by Hattori A., et al. Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase.
PMID: 11481040 by Hattori A., et al. Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene.