Gamma-enolase Antibodies

AND ENO2 ELISA kits, Gamma-enolase Proteins

Many biological assays use antibodies to detect Gamma-enolase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gamma-enolase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gamma-enolase antibodies...

We validate the specificity of these antibodies to Gamma-enolase by testing them on tissues known to express ENO2 positively and negatively. Browse below to find the ENO2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ENO2 Infographic by Boster Bio

All ENO2 Products

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Anti-NSE/ENO2 Antibody Picoband®

15 Citations 1 Q&As

Anti-NSE antibody, PA1061, Western blottingWB: Rat Brain Tissue Lysate

IHC analysis of NSE/ENO2 using anti-NSE/ENO2 antibody (PA1061)

Macroscopic examination of the CAM and implanted human NCI-H446 cells

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1061
100 μg/vial

Anti-NSE ENO2 Rabbit Monoclonal Antibody

7 Citations

Western blot analysis of NSE expression in HeLa cell lysate

Immunohistochemical analysis of paraffin-embedded human uterus cancer, using NSE Antibody

Immunofluorescent analysis of A431 cells, using NSE Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02930-1
100 μl

Anti-NSE/ENO2 Antibody Picoband®

25 Citations

Western blot analysis of NSE/ENO2 using anti-NSE/ENO2 antibody (A02930)

IHC analysis of NSE/ENO2 using anti-NSE/ENO2 antibody (A02930)

IHC analysis of NSE using anti-NSE antibody (A02930)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02930
100 μg/vial

Mouse Enolase 2/Neuron-specific Enolase Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Enzyme Activity, SDS-PAGE

$265
Cat # PROTP17183
Starting from 10ug

NSE (ENO2) (NM_001975) Human Over-expression Lysate

Human

$628
Cat # LS002026
20 µg, 100 µg

ENO2 Overview

Facts about Gamma-enolase.

ENO2 3D structure. Source: alphafold

Gamma-enolase (ENO2)

Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).

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Gene Information

Human
Gene Name:	ENO2
Uniprot:	P09104
Entrez:	2026

Family

Belongs to:

enolase family

Alternative Names

2-phospho-D-glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; EC 4.2.1.11; ENO2; enolase 2 (gamma, neuronal); Enolase 2; gamma-Enolase; Neural enolase; neuron specific gamma enolase; neurone-specific enolase; Neuronspecific Enolase; Neuron-specific enolase; NSE

Molecular Weight

Mass (kDA):
47.269 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (6914580..6923697)

Tissue Specificity

The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

Subcellular Localizations

Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.

Diseases

Malignant Neoplasms
Neoplasms
Hypoxia
Schizophrenia
Neoplasm Metastasis
Malignant Tumor Of Cervix
Carcinoma
Tumor Angiogenesis
Toxoplasmosis, Animal
Mental Disorders
Small Cell Carcinoma Of Lung
Prostatic Neoplasms
Uterine Cervical Neoplasm

Anoxia
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Hypertensive Disease
Toxoplasmosis
Stomach Neoplasms
Essential Hypertension

Interacting Proteins

TINF2

Pathways

Glycolysis
Localization
Translation
Pathogenesis
Gluconeogenesis
Cell Cycle
Mating
Angiogenesis
Transport
Hyperphosphorylation
Cell Migration
Gene Silencing
Stem Cell Differentiation

Immune Response
Neurogenesis
Regulation Of Gene Expression
Histone Modification
Virulence
Metestrus
Embryo Development

PTMs

Phosphorylation
Oxidation

Nitration
Dephosphorylation

Research Areas

Cancer
Cellular Markers
Neuronal Cell Markers
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENO2

References

PMID: 3208766 by McAleese S.M., et al. Complete amino acid sequence of the neurone-specific gamma isozyme of enolase (NSE) from human brain and comparison with the non-neuronal alpha form (NNE).

PMID: 3385803 by van Obberghen E., et al. Human gamma enolase: isolation of a cDNA clone and expression in normal and tumor tissues of human origin.

63 Publications of Boster Gamma-enolase Antibodies & ELISA Kits

PubMed ID: PMID:25197353, Effects of transforming growth factor-β2 on myocilin expression and secretion i...
PubMed ID: 10.5114/fn.2018.76615, The impact of bone marrow-derived mesenchymal stem cells on neovascularisation i...
PubMed ID: 10.4103/1673-5374.211193, Protective effects of Dendrobium nobile Lindl. alkaloids on amyloid beta (25–3...
PubMed ID: 10.4103/1673-5374.139460, Optimal therapeutic dose and time window of picroside II in cerebral ischemic in...
PubMed ID: 10.3969/j.issn.1673-5374.2013.10.005, Injury of cortical neurons is caused by the advanced glycation end products-medi...
PubMed ID: 10.3892/or.16.5.1021, Histological type of oncogenity and expression of cell cycle genes in tumor cell...
PubMed ID: 10.3892/ijo.2014.2448, β-elemene inhibits stemness, promotes differentiation and impairs chemoresistan...
PubMed ID: 10.3892/ijmm.2011.734, Involvement of calmodulin and actin in directed differentiation of rat cortical ...
PubMed ID: 10.3389/fneur.2016.00183, In Vitro Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-Like ...
PubMed ID: 10.3109/13880209.2013.877039, Neuroprotective effects of oxysophocarpine on neonatal rat primary cultured hipp...
PubMed ID: 10.3109/10717544.2011.596583, Brain targeting and toxicity study of odorranalectin-conjugated nanoparticles fo...
PubMed ID: 10.3109/02713680903128935, Modulation of Migration and Ca2+ Signaling in Retinal Pigment Epithelium Cells b...
PubMed ID: 10.3109/02699052.2011.568035, Protective effects of early hypoxic post-conditioning in cultured cortical neuro...
PubMed ID: 10.1177/0963689719883578, HBO Promotes the Differentiation of Neural Stem Cells via Interactions Between t...
PubMed ID: 10.1155/2017/7842082, Neuroprotective Effect of the Ginsenoside Rg1 on Cerebral Ischemic Injury In Viv...
PubMed ID: 10.1111/j.1745-7254.2007.00512.x, Stearic acid protects primary cultured cortical neurons against oxidative stress...
PubMed ID: 10.1016/S1673-5374(07)60010-3, Protective effect of Angelica sinensis on cerebral neurons from rat embryos unde...
PubMed ID: 10.1016/j.jpedsurg.2007.03.050, The structural characteristics and expression of neuropeptides in the esophagus ...
PubMed ID: 10.1016/j.ijpharm.2007.03.039, UEA I-bearing nanoparticles for brain delivery following intranasal administrati...
PubMed ID: 10.1016/j.cellbi.2006.11.012, Ex vivo expansion, adipogenesis and neurogenesis of cryopreserved human bone mar...
PubMed ID: 10.1016/j.bbrc.2010.09.107, Differentiation of neural stem cells into Schwann-like cells in vitro

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page