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- Table of Contents
FGF19 Antibodies
AND FGF19 ELISA kits, FGF19 Proteins
Many biological assays use antibodies to detect FGF19, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FGF19 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FGF19 antibodies...
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FGF19 Infographic by Boster Bio
All FGF19 Products
Product
Figures
Specificity
Applications
Price
Human FGF19 ELISA Kit PicoKine®
1 Citations 8 Q&As
Human
ELISA
$499
Cat # EK1160
96 wells/kit, with removable strips.
Cat # EK1160
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ1160
For 5 plates, 96 wells each
Cat # EZ1160
For 5 plates, 96 wells each
Human
Cell Culture
$77
Cat # PROTO95750-4
5ug,20ug,100ug
Cat # PROTO95750-4
5ug,20ug,100ug
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01191-1
100 μg
Cat # M01191-1
100 μg
FGF19 Overview
Facts about Fibroblast growth factor 19.
Fibroblast growth factor 19 (FGF19)
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, after positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes.
Activity requires the presence of KLB and FGFR4. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FGF19 |
| Uniprot: | O95750 |
| Entrez: | 9965 |
Family
| Belongs to: |
|---|
| heparin-binding growth factors family |
Alternative Names
FGF19; FGF-19; fibroblast growth factor 19
Molecular Weight
Mass (kDA):
24.003 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.3 |
| Sequence: | 11; NC_000011.10 (69698238..69704022, complement) |
Tissue Specificity
Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Diabetes Mellitus
- Liver Carcinoma
- Obesity
- Diarrhea
- Malabsorption Syndrome
- Diabetes Mellitus, Non-insulin-dependent
- Chronic Diarrhea
- Insulin Resistance
- Liver Neoplasms
Pathways
- Cell Proliferation
- Pathogenesis
- Transport
- Secretion
- Glucose Homeostasis
- Lipid Homeostasis
- Energy Homeostasis
- Localization
- Gluconeogenesis
- Hepatocyte Proliferation
- Cell Growth
- Eye Development
- Regulation Of Glucose Homeostasis
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FGF19
bosterbio.com/bosterbio-gene-info-cards/FGF19
References
PMID: 9931477 by Nishimura T., et al. Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain.
PMID: 10525310 by Xie M.-H., et al. FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4.
1 Publications of Boster FGF19 Antibodies & ELISA Kits
- PubMed ID: 10.5114/aoms.2017.72424, Evaluation of FGF-19 and β-klotho as biomarkers in patients with intrahepatic c...
*More publications can be found for each product on its corresponding product page