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- Table of Contents
Lactoylglutathione lyase Antibodies
AND GLO1 ELISA kits, Lactoylglutathione lyase Proteins
Many biological assays use antibodies to detect Lactoylglutathione lyase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lactoylglutathione lyase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lactoylglutathione lyase antibodies...
Designing a Western blot for Lactoylglutathione lyase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GLO1 Western Blot GuideDesigning an IHC experiment for Lactoylglutathione lyase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GLO1 IHC GuideGLO1 Infographic by Boster Bio
All GLO1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IP, IF, IHC, ICC, WB
$370
Cat # A01703-1
100 μg/vial
Cat # A01703-1
100 μg/vial
Enzyme Activity, SDS-PAGE
$265
Cat # PROTQ9CPU0
Starting from 10ug
Cat # PROTQ9CPU0
Starting from 10ug
Enzyme Activity, SDS-PAGE
$218
Cat # PROTQ04760
Starting from 4ug
Cat # PROTQ04760
Starting from 4ug
GLO1 Overview
Facts about Lactoylglutathione lyase.
Lactoylglutathione lyase (GLO1)
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B.
Required for normal osteoclastogenesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GLO1 |
| Uniprot: | Q04760 |
| Entrez: | 2739 |
Family
| Belongs to: |
|---|
| glyoxalase I family |
Alternative Names
Aldoketomutase; EC 4.4.1.5; GLO1; GLOD1; Glx I; GLYI; glyoxalase domain containing 1; Glyoxalase I; glyoxalase Ialdoketomutase; Ketone-aldehyde mutase; lactoyl glutathione lyase; lactoylglutathione lyase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
Molecular Weight
Mass (kDA):
20.778 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.2 |
| Sequence: | 6; NC_000006.12 (38675925..38703145, complement) |
Diseases
- Diabetes Mellitus
- Anxiety Disorders
- Malignant Neoplasms
- Neoplasms
- Hyperglycemia
- Schizophrenia
- Autistic Disorder
- Carcinoma
- Diabetes Mellitus, Non-insulin-dependent
- Depressive Disorder
- Persistant Generalized Lymphadenopathy
- Ataxia
Pathways
- Glycolysis
- Pathogenesis
- Localization
- Aging
- Reverse Transcription
- Cell Proliferation
- Excretion
- Response To Methylglyoxal
- Senescence
- Secretion
- Cerebral Cortex Development
- Cellular Senescence
- Immune Response
PTMs
- Phosphorylation
- Glutathionylation
Research Areas
- Cancer
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLO1
bosterbio.com/bosterbio-gene-info-cards/GLO1
References
PMID: 7684374 by Kim N.-S., et al. Human glyoxalase I. cDNA cloning, expression, and sequence similarity to glyoxalase I from Pseudomonas putida.
PMID: 8449929 by Ranganathan S., et al. Cloning and characterization of human colon glyoxalase-I.