GRB2 Antibodies

AND GRB2 ELISA kits, GRB2 Proteins

Many biological assays use antibodies to detect GRB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRB2 antibodies...

We validate the specificity of these antibodies to GRB2 by testing them on tissues known to express GRB2 positively and negatively. Browse below to find the GRB2 antibody that suites your experiment. We have 22 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GRB2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the GRB2 Western Blot Guide

Designing an IHC experiment for GRB2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the GRB2 IHC Guide

GRB2 Infographic by Boster Bio

All GRB2 Products

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Product

Figures

Specificity

Applications

Price

Anti-GRB2 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M00351-2
100 µl/vial

Anti-FAM59B GAREM2 Antibody

Western blot analysis of FAM59B in SK-N-SH cell lysate with FAM59B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of FAM59B in human brain tissue with FAM59B antibody at 5 μg/mL

Immunofluorescence of FAM59B in Human Brain cells with FAM59B antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A17028
0.1 mg

Anti-FAM59A GAREM1 Antibody

Western blot analysis of FAM59A in rat liver tissue lysate with FAM59A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of PLEKHM3 in human brain tissue with PLEKHM3 antibody at 5 μg/mL

Immunofluorescence of FAM59A in Human Liver cells with FAM59A antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A12630
0.1 mg

Anti-Endophilin-B1 SH3GLB1 Antibody

Immunofluorescence analysis of A549 cells using Bif-1 antibody

Human

IF, ICC, WB

$405
Cat # A04792-1
100ul

GRB2 (NM_002086) Human Over-expression Lysate

GRB2 Human Over-expression Lysates NM_002086

Human

$628
Cat # LS002885
20 µg, 100 µg

Anti-GRB2 Antibody Picoband®

Western blot analysis of GRB2 using anti-GRB2 antibody (A00351-1)

Flow Cytometry analysis of PC-3 cells using anti-GRB2 antibody (A00351-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A00351-1
100 μg/vial

Anti-Bif SH3GLB1 Antibody

Western blot analysis of BIF in HeLa cell lysate with BIF antibody at (A) 1 and (B) 2 μg/mL

Immunocytochemistry of BIF in HeLa with BIF antibody at 10 μg/mL

Human, Mouse

ELISA, ICC, WB

$481
Cat # A04792
0.1 mg

Anti-GAB1 Antibody Picoband®

Western blot analysis of GAB1 using anti-GAB1 antibody (A01989-1)

Human, Mouse, Rat

$370
Cat # A01989-1
100 μg/vial

Anti-SH3GL3 Antibody (C-term)

Human

$299
Cat # M09836
80 µl

Anti-Endophilin-A3 SH3GL3 Antibody

Western blot analysis of various lysates, using SH3GL3 antibody at 1:1000 dilution

Human, Mouse, Rat

IHC, WB

$405
Cat # A09836
100ul

Anti-Endophilin-A2 SH3GL1 Antibody

Western blot analysis of extracts of COS-7 cells, using SH3GL1 antibody at 1:1000 dilution

Human, Monkey, Mouse, Rat

IHC, WB

$405
Cat # A05946
100ul

Anti-GRB2 Monoclonal Antibody

Western blot analysis of GRB2 expression in HEK293 cell lysate

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M00351
100 μl

Human GRAP2 Recombinant Protein

SDS-PAGE

$265
Cat # PROTO75791
Starting from 10ug

Anti-GRB2 Antibody (Y209)

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GRB2 Antibody (Y209), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining

Western blot analysis of lysate from Ramos cell line, using GRB2 Antibody (pY209)

Human

IHC-P, WB

$299
Cat # A00351
80 µl

GRB2 (Phospho-Ser159) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HT29 cells treated with serum 20% 15

Human, Mouse, Rat

ELISA

$540
Cat # EKC2598
1 kit, containing two 96-well plates and all necessary reagents

Gab2 (Phospho-Ser623) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HepG2 cells treated with PMA 125ng/ml 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2615
1 kit, containing two 96-well plates and all necessary reagents

Gab2 (Phospho-Tyr643) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from Jurkat cells treated with IFN 2500U/ML 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2614
1 kit, containing two 96-well plates and all necessary reagents

GAB1 (Phospho-Tyr627) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HuvEc cells treated with EGF 200ng/ml 10

Human, Mouse

ELISA

$540
Cat # EKC2415
1 kit, containing two 96-well plates and all necessary reagents

Phospho-GAB1 (Tyr659) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from NIH-3T3 cells treated with Insulin 0

Human, Mouse, Rat

ELISA

$540
Cat # EKC2196
1 kit, containing two 96-well plates and all necessary reagents

Gab2 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from Jurkat cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1229
1 kit, containing one 96-well plate and all necessary reagents

Anti-Gab 2/4 GAB4 Antibody

Human

ELISA, IF, IHC, WB

$380
Cat # A19486
100ul

Human GRB2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP62993
Starting from 20ug

GRB2 Overview

Facts about Growth factor receptor-bound protein 2.

GRB2 3D structure. Source: alphafold

Growth factor receptor-bound protein 2 (GRB2)

Adapter protein that provides a critical connection between cell surface growth factor receptors and the Ras signaling pathway. .

Gene Information

Human
Gene Name:	GRB2
Uniprot:	P62993
Entrez:	2885

Family

Belongs to:

GRB2/sem-5/DRK family

Alternative Names

abundant SRC homology; Adapter protein GRB2; ASH; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; GRB2; Grb3-3; growth factor receptor-bound protein 2; growth factor receptor-bound protein 3; HT027; MST084; MSTP084; NCKAP2; Protein Ash; SH2/SH3 adapter GRB2

Molecular Weight

Mass (kDA):
25.206 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (75318076..75405709, complement)

Subcellular Localizations

Nucleus. Cytoplasm. Endosome. Golgi apparatus.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Cell Transformation, Neoplastic
Leukemia
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Myeloid Leukemia
Myeloid Leukemia, Chronic
Metaplastic Cell Transformation
Neoplasm Metastasis
Cell Invasion

Malignant Paraganglionic Neoplasm
Lymphoma
Tumor Angiogenesis
Janiceps
Hyperplasia
Chimera Disorder
Nervousness

Pathways

Cell Proliferation
Cell Growth
Localization
Cell Activation
Endocytosis
Cell Cycle
Cell Migration
Pathogenesis
T Cell Activation
Cell Adhesion
Cell Death
Secretion
Angiogenesis

Cell Motility
Cell Differentiation
Transport
Rna Interference
Cell Development
Mitosis
Intracellular Signal Transduction

PTMs

Phosphorylation
Dephosphorylation
Ubiquitination
Cleavage
Myristoylation
Biotinylation
Reduction
Palmitoylation
Glycosylation

Oxidation
Ribosylation
Farnesylation
Methylation
Hydroxylation
Prenylation
Acylation
Iodination
Acetylation

Deglycosylation

Research Areas

Angiogenesis
Breast Cancer
Cancer
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRB2

References

PMID: 1322798 by Lowenstein E.J., et al. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

PMID: 1384039 by Matuoka K., et al. Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries.