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- Table of Contents
HIP1R Antibodies
AND HIP1R ELISA kits, HIP1R Proteins
Many biological assays use antibodies to detect HIP1R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HIP1R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HIP1R antibodies...
Designing a Western blot for HIP1R? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HIP1R Western Blot GuideDesigning an IHC experiment for HIP1R? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HIP1R IHC GuideHIP1R Infographic by Boster Bio
All HIP1R Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05059-2
100 μg/vial
Cat # A05059-2
100 μg/vial
HIP1R Overview
Facts about Huntingtin-interacting protein 1-related protein.
Huntingtin-interacting protein 1-related protein (HIP1R)
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (through ENTH domain).
May act through the ENTH domain name to promote cell survival by stabilizing receptor tyrosine kinases after ligand-induced endocytosis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HIP1R |
| Uniprot: | O75146 |
| Entrez: | 9026 |
Family
| Belongs to: |
|---|
| SLA2 family |
Alternative Names
FLJ14000; HIP-12; HIP12HIP1-related protein; HIP3; huntingtin interacting protein 1 related; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ; KIAA0655FLJ27022; MGC47513
Molecular Weight
Mass (kDA):
119.388 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.31 |
| Sequence: | 12; NC_000012.12 (122834498..122862961) |
Tissue Specificity
Brain, heart, kidney, pancreas, and liver, but not in lung or placenta.
Subcellular Localizations
Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.
Diseases
- Parkinson Disease
- Huntington Disease
- Tissue Adhesions
- Hypertrophy
- Metaplasia
- Malignant Neoplasms
- Dwarfism
- Bipolar Disorder
- Mucinous Adenocarcinoma
- Leukemia
- Metaplastic Cell Transformation
- Stomach Neoplasms
Pathways
- Endocytosis
- Clathrin-mediated Endocytosis
- Localization
- Transport
- Cell Death
- Cell Adhesion
- Translation
- Receptor-mediated Endocytosis
- Membrane Invagination
- Rna Interference
- Hyperphosphorylation
- Interaction With Host
- Aging
PTMs
- Phosphorylation
Research Areas
- Cancer
- Cell Biology
- Neurodegeneration
- Neuronal Cell Markers
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIP1R
bosterbio.com/bosterbio-gene-info-cards/HIP1R
References
PMID: 11063258 by Chopra V.S., et al. HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin.
PMID: 9852681 by Seki N., et al. Cloning, expression analysis, and chromosomal localization of HIP1R, an isolog of huntingtin interacting protein (HIP1).