Holliday junction recognition protein (HJURP)

Centromeric protein which plays a central role in the incorporation and maintenance of histone H3-like version CENPA in centromeres. Acts as a specific chaperone for CENPA and is necessary for the incorporation of newly synthesized CENPA molecules to nucleosomes at replicated centromeres.

Prevents CENPA-H4 tetramerization and prevents premature DNA binding from the CENPA-H4 tetramer. Directly binds Holliday junctions.