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- Table of Contents
Integrin alpha-5 Antibodies
AND ITGA5 ELISA kits, Integrin alpha-5 Proteins
Many biological assays use antibodies to detect Integrin alpha-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-5 antibodies...
Designing a Western blot for Integrin alpha-5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGA5 Western Blot GuideITGA5 Infographic by Boster Bio
All ITGA5 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$750
Cat # EK2227
96 wells/kit, with removable strips.
Cat # EK2227
96 wells/kit, with removable strips.
Anti-Integrin alpha 5/ITGA5 Antibody Picoband®
4 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A01911
100 μg/vial
Cat # A01911
100 μg/vial
Anti-Tlr6 Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01914-2
100 μg/vial
Cat # A01914-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01911
100 μl
Cat # M01911
100 μl
Mouse
Flow Cytometry, IHC-F, ICC
$299
Cat # M01911-1
0.1 mg
Cat # M01911-1
0.1 mg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01911-4
100 μg
Cat # M01911-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01911-3
100 μg
Cat # M01911-3
100 μg
Human
$628
Cat # LS003678
20 µg, 100 µg
Cat # LS003678
20 µg, 100 µg
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A01911-1
100ul
Cat # A01911-1
100ul
ITGA5 Overview
Facts about Integrin alpha-5.
Integrin alpha-5 (ITGA5)
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands.
ITGA5:ITGB1 binds to PLA2G2A by means of a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and improved ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 functions as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGA5 |
| Uniprot: | P08648 |
| Entrez: | 3678 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
Integrin alpha 5 beta 1; VLA-5
Molecular Weight
Mass (kDA):
114.536 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (54395261..54419266, complement) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Cell surface.
Interacting Proteins
- ENG
- ITGB1
- NRP1
- Nrp1
- SHARPIN
PTMs
- Cleavage on pair of basic residues
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA5
bosterbio.com/bosterbio-gene-info-cards/ITGA5
References
PMID: 2958481 by Argraves W.S., et al. Amino acid sequence of the human fibronectin receptor.
PMID: 1834647 by Birkenmeier T.M., et al. The alpha 5 beta 1 fibronectin receptor. Characterization of the alpha 5 gene promoter.
5 Publications of Boster Integrin alpha-5 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.ijcard.2013.01.239, Calreticulin overexpression correlates with integrin-α5 and transforming growth...
- PubMed ID: 26680220, Silencing of Paternally Expressed Gene 10 Inhibits Trophoblast Proliferation and...
- PubMed ID: 24643246, A Small Physiological Electric Field Mediated Responses of Extravillous Trophobl...
- PubMed ID: 19918321, Characterization of Rat Hair Follicle Stem Cells Selected by Vario Magnetic Acti...
- PubMed ID: 2775103, Characterization of Rat Hair Follicle Stem Cells Selected by Vario Magnetic Acti...
*More publications can be found for each product on its corresponding product page