This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Integrin beta-4 Antibodies
AND ITGB4 ELISA kits, Integrin beta-4 Proteins
Many biological assays use antibodies to detect Integrin beta-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin beta-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin beta-4 antibodies...
Designing a Western blot for Integrin beta-4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGB4 Western Blot GuideITGB4 Infographic by Boster Bio
All ITGB4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03727
100 μg/vial
Cat # M03727
100 μg/vial
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # M03603
100 μg/vial
Cat # M03603
100 μg/vial
Human, Mouse, Rat
IHC, ICC, WB
$370
Cat # PB9582
100 μg/vial
Cat # PB9582
100 μg/vial
Human, Monkey
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03813-1
100 μg/vial
Cat # M03813-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03639-1
100 μg/vial
Cat # M03639-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03639
100 μg/vial
Cat # M03639
100 μg/vial
Anti-CD20 Antibody Picoband® (monoclonal, 4D11)
1 Citations
Human
IF, IHC, WB
$370
Cat # M03780-5
100 μg/vial
Cat # M03780-5
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M03727-2
100 μg/vial
Cat # M03727-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03735-1
100 μg/vial
Cat # M03735-1
100 μg/vial
Human
IF, WB
$370
Cat # M03780-4
100 μg/vial
Cat # M03780-4
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M03727-1
100 μg/vial
Cat # M03727-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03642-2
100 μg/vial
Cat # M03642-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M03581
100 μg/vial
Cat # M03581
100 μg/vial
Human
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9007
100 μg/vial
Cat # PB9007
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2031
100 μg/vial
Cat # PA2031
100 μg/vial
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M01015-2
100 μg/vial
Cat # M01015-2
100 μg/vial
Anti-Integrin beta 4/ITGB4 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01015-2
100 μg/vial
Cat # A01015-2
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A01015Y1510
100ul
Cat # A01015Y1510
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2303
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2303
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1305
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1305
1 kit, containing one 96-well plate and all necessary reagents
Human
$960
Cat # LS003691
20 µg, 100 µg
Cat # LS003691
20 µg, 100 µg
ITGB4 Overview
Facts about Integrin beta-4.
Integrin beta-4 (ITGB4)
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells.
Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778).
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGB4 |
| Uniprot: | P16144 |
| Entrez: | 3691 |
Family
| Belongs to: |
|---|
| integrin beta chain family |
Alternative Names
CD104 antigen; CD104; GP150; Integrin beta 4; integrin beta-4 subunit; integrin beta-4; integrin, beta 4; ITGB4
Molecular Weight
Mass (kDA):
202.167 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q25.1 |
| Sequence: | 17; NC_000017.11 (75721339..75757819) |
Tissue Specificity
Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Colocalizes with DST at the leading edge of migrating keratinocytes.
Diseases
- Epidermolysis Bullosa
- Atresia
- Malignant Neoplasms
- Junctional Epidermolysis Bullosa
- Bulla
- Tissue Adhesions
- Epidermolysis Bullosa Junctionalis With Pyloric Atresia
- Neoplasms
- Neoplasm Metastasis
- Carcinoma
- Cell Invasion
Interacting Proteins
- ARRDC3
- ITGA6
- PLEC
- PTK2
- S1PR2
- S1PR3
Pathways
- Cell Adhesion
- Cell Proliferation
- Cell Migration
- Immune Response
- Translation
- Pathogenesis
- Cell Cycle
- Invasive Growth
- Cell Growth
- Angiogenesis
- Transport
- Cell Activation
- Neutrophil Extravasation
PTMs
- Disulfide bond
- Glycoprotein
Research Areas
- Adaptive Immunity
- Immunology
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGB4
bosterbio.com/bosterbio-gene-info-cards/ITGB4
References
PMID: 2311577 by Suzuki S., et al. Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.
PMID: 2311578 by Hogervorst F., et al. Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain.