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- Table of Contents
Facts about Intermediate conductance calcium-activated potassium channel protein 4.
Required for maximum calcium influx and proliferation throughout the reactivation of innocent T-cells (PubMed:17157250, PubMed:18796614). Plays a role in the late stages of EGF-induced macropinocytosis (PubMed:24591580).
Human | |
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Gene Name: | KCNN4 |
Uniprot: | O15554 |
Entrez: | 3783 |
Belongs to: |
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potassium channel KCNN family |
hIKCa1; hKCa4; hSK4; IK1; IKCa1; intermediate conductance calcium-activated potassium channel protein 4; KCa3.1IKCA1; KCa4; KCA4SKCa4; potassium intermediate/small conductance calcium-activated channel, subfamilyN, member 4; putative erythrocyte intermediate conductance calcium-activated potassiumGardos channel; Putative Gardos channel; SK4SKCa 4
Mass (kDA):
47.696 kDA
Human | |
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Location: | 19q13.31 |
Sequence: | 19; NC_000019.10 (43766533..43782139, complement) |
Widely expressed in non-excitable tissues.
Cell membrane; Multi-pass membrane protein.
PMID: 9380751 by Joiner W.J., et al. hSK4, a member of a novel subfamily of calcium-activated potassium channels.
PMID: 9326665 by Ishii T.M., et al. A human intermediate conductance calcium-activated potassium channel.