Kallikrein-4 Antibodies

AND KLK4 ELISA kits, Kallikrein-4 Proteins

Many biological assays use antibodies to detect Kallikrein-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kallikrein-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kallikrein-4 antibodies...

We validate the specificity of these antibodies to Kallikrein-4 by testing them on tissues known to express KLK4 positively and negatively. Browse below to find the KLK4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Kallikrein-4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the KLK4 Western Blot Guide

Designing an IHC experiment for Kallikrein-4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the KLK4 IHC Guide

KLK4 Infographic by Boster Bio

All KLK4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Kallikrein 4/KLK4 Antibody Picoband®

Anti-Picoband antibody, PB, Western blottingAll lanes: Anti Kallikrein 4 (PB9260) at 0

Human

$370
Cat # PB9260
100 μg/vial

Anti-Kallikrein-4 KLK4 Antibody

Western blot analysis of KLK4 in human kidney tissue lysate with KLK4 antibody at 1 μg/ml

Human

ELISA, IF, IHC-P, WB

$481
Cat # A03430
0.1 mg

Kallikrein 4 (KLK4) (NM_004917) Human Over-expression Lysate

Human

$628
Cat # LS009622
20 µg, 100 µg

KLK4 Overview

Facts about Kallikrein-4.

KLK4 3D structure. Source: alphafold

Kallikrein-4 (KLK4)

Has a significant role in tooth formation (PubMed:15235027). Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity).

Gene Information

Human
Gene Name:	KLK4
Uniprot:	Q9Y5K2
Entrez:	9622

Family

Belongs to:

peptidase S1 family

Alternative Names

AI2A1; ARM1; EC 3.4.21; EC 3.4.21.-; EMSP; EMSP1; EMSP1MGC116827; Enamel matrix serine proteinase 1; kallikrein 4 (prostase, enamel matrix, prostate); Kallikrein 4; kallikrein-4; Kallikrein-like protein 1; kallikrein-related peptidase 4; KLK4; KLK-L1MGC116828; Prostase; PRSS17enamel matrix serine protease 1; PSTSandrogen-regulated message 1; Serine protease 17

Molecular Weight

Mass (kDA):
27.032 kDA

Genomic Context


Human

Location:	19q13.41
Sequence:	19; NC_000019.10 (50906352..50910745, complement)

Tissue Specificity

Expressed in prostate.

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Neoplasms
Amelogenesis Imperfecta
Malignant Paraganglionic Neoplasm
Carcinoma
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Adenocarcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms

Endometrial Polyp
Dental Enamel Hypoplasia
Cell Invasion
Endometrial Carcinoma
Hyperplasia
Neoplasm Metastasis
Dental Fluorosis, Acquired

Interacting Proteins

TYRO3

Pathways

Amelogenesis
Localization
Pathogenesis
Secretion
Proteolysis
Dentinogenesis
Protein Secretion
Translation
Enamel Mineralization
Cell Proliferation
Odontogenesis
Cell Migration
Reverse Transcription

Cell Growth
Cell Adhesion
Dentin Mineralization
Pigmentation
Cell Cycle
Tissue Morphogenesis
Glycosylation

PTMs

Cleavage
Phosphorylation

Glycosylation
Deglycosylation

Research Areas

Apoptosis
Cancer
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLK4

References

PMID: 10077646 by Nelson P.S., et al. Molecular cloning and characterization of prostase, an androgen- regulated serine protease with prostate-restricted expression.

PMID: 10485467 by Yousef G.M., et al. Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated.