Anti-Kallikrein-4 KLK4 Antibody

Kallikrein 4/Prostase/EMSP1 antibody

Boster Bio Anti-Kallikrein-4 KLK4 Antibody (Catalog # A03430). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Product Info Summary

SKU: A03430
Size: 0.1 mg
Reactive Species: Human
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-Kallikrein-4 KLK4 Antibody

View all Kallikrein 4/Prostase/EMSP1 Antibodies

SKU/Catalog Number

A03430

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Kallikrein-4 KLK4 Antibody (Catalog # A03430). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Storage & Handling

KLK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Kallikrein-4 KLK4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03430)

Host

Rabbit

Contents

KLK4 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

KLK4 antibody was raised against a 15 amino acid peptide near the center of human KLK4. The immunogen is located within amino acids 80 - 130 of KLK4 .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

KLK4 antibody is human specific. At least three isoforms of KLK4 are known to exist.

Reactive Species

A03430 is reactive to KLK4 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

27032 MW

Background of Kallikrein 4/Prostase/EMSP1

Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions (1). Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers (3). KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A03430 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

KLK4 antibody can be used for detection of KLK4 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For KLK4 (Source: Uniprot.org, NCBI)

Gene Name

KLK4

Full Name

Kallikrein-4

Weight

27032 MW

Superfamily

peptidase S1 family

Alternative Names

ARM1, EMSP, PSTS, AI2A1, EMSP1, KLK-L1, PRSS17, kallikrein, Kallikrein-4, Enamel matrix serine proteinase 1 KLK4 AI2A1, ARM1, EMSP, EMSP1, KLK-L1, PRSS17, PSTS, kallikrein kallikrein related peptidase 4 kallikrein-4|androgen-regulated message 1|enamel matrix serine protease 1|enamel matrix serine proteinase 1|kallikrein-like protein 1|prostase|serine protease 17

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on KLK4, check out the KLK4 Infographic

KLK4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KLK4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03430-0.1 mg

0.1 mg

$449

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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