NDUFA12 Antibodies

AND NDUFA12 ELISA kits, NDUFA12 Proteins

Many biological assays use antibodies to detect NDUFA12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFA12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFA12 antibodies...

We validate the specificity of these antibodies to NDUFA12 by testing them on tissues known to express NDUFA12 positively and negatively. Browse below to find the NDUFA12 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDUFA12 Infographic by Boster Bio

All NDUFA12 Products

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Anti-NDUFA12 Antibody

Western blot analysis of extracts of various cell lines, using NDUFA12 antibody at 1:3000 dilution

Human, Mouse, Rat

$405
Cat # A10519
100ul

DAP13 (NDUFA12) (NM_018838) Human Over-expression Lysate

Human

$628
Cat # LS055967
20 µg, 100 µg

NDUFA12 Overview

Facts about NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12.

NDUFA12 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (NDUFA12)

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone. .

Gene Information

Human
Gene Name:	NDUFA12
Uniprot:	Q9UI09
Entrez:	55967

Family

Belongs to:

complex I NDUFA12 subunit family

Alternative Names

13 kDa differentiation-associated protein; B17.2,13kDa differentiation-associated protein; CIB17.2; CI-B17.2; complex I B17.2 subunit; Complex I-B17.2; DAP13NADH-ubiquinone oxidoreductase subunit B17.2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; NADH: ubiquinone oxidoreductase

Molecular Weight

Mass (kDA):
17.114 kDA

Genomic Context


Human

Location:	12q22
Sequence:	12; NC_000012.12 (94971328..95003713, complement)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Mitochondrial Diseases
Tissue Adhesions
Alzheimer's Disease
Leigh Disease
Dysequilibrium Syndrome

Pathways

Cell Adhesion
Immune Response
Endocytosis
Oxidative Phosphorylation
Iron-sulfur Cluster Assembly

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFA12

References

PMID: 10830904 by Triepels R., et al. Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I- deficient-patients.

PMID: 21617257 by Ostergaard E., et al. Respiratory chain complex I deficiency due to NDUFA12 mutations as a new cause of Leigh syndrome.