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Nhej1 Antibodies
AND Nhej1 ELISA kits, Nhej1 Proteins
Many biological assays use antibodies to detect Nhej1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nhej1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nhej1 antibodies...
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Nhej1 Infographic by Boster Bio
All Nhej1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03552-3
100 μg/vial
Cat # A03552-3
100 μg/vial
Human, Monkey
Flow Cytometry, IF, IHC, WB
$523
Cat # M03552
100 µl
Cat # M03552
100 µl
Dog, Human, Monkey, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03552-1
100 µl
Cat # M03552-1
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03552-2
100 μl/vial
Cat # M03552-2
100 μl/vial
Nhej1 Overview
Facts about Non-homologous end-joining factor 1.
Non-homologous end-joining factor 1 (Nhej1)
DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and another NHEJ factors located at DNA ends, or may participate in reconfiguration of the conclusion bound NHEJ factors to permit XRCC4 access to the DNA termini.
It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several kinds of mismatched ends that are noncomplementary or partially complementary (PubMed:17360556). Binds DNA in a length-dependent way (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nhej1 |
| Uniprot: | Q3KNJ2 |
| Entrez: | 75570 |
Family
| Belongs to: |
|---|
| XLF family |
Alternative Names
Cernunnos; non-homologous end-joining factor 1; nonhomologous end-joining factor 1; Protein cernunnos; XLFFLJ12610; XRCC4-like factor
Molecular Weight
Mass (kDA):
32.739 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 1|1 C4 |
| Sequence: | 1; |
Diseases
- Immunologic Deficiency Syndromes
- Malignant Neoplasms
- Severe Combined Immunodeficiency
- Microcephaly
- Neoplasms
- Chromosomal Translocation
- Congenital Combined Immunodeficiency
- Lymphoma
- Lymphopenia
- Growth Retardation
- Ataxia Telangiectasia
- Nijmegen Breakage Syndrome
- Infective Disorder
Pathways
- Dna Repair
- V(d)j Recombination
- Double-strand Break Repair
- Aging
- Dna Ligation
- Dna Replication
- Cell Cycle
- Transport
- Circadian Rhythm
- Hypersensitivity
- Donor Selection
- Carbohydrate Utilization
PTMs
Research Areas
- Cancer
- Chromatin Research
- DNA Repair
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nhej1
bosterbio.com/bosterbio-gene-info-cards/Nhej1
References
PMID: 17360556 by Zha S., et al. Defective DNA repair and increased genomic instability in Cernunnos- XLF-deficient murine ES cells.