NR2E3 Antibodies

AND NR2E3 ELISA kits, NR2E3 Proteins

Many biological assays use antibodies to detect NR2E3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NR2E3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NR2E3 antibodies...

We validate the specificity of these antibodies to NR2E3 by testing them on tissues known to express NR2E3 positively and negatively. Browse below to find the NR2E3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NR2E3 Infographic by Boster Bio

All NR2E3 Products

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Product

Figures

Specificity

Applications

Price

Anti-NR2E3 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A01983
100ul

Anti-NR2E3 Mouse Monoclonal Antibody [Clone ID: OTI3D4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR2E3 (Right lane) cDNA for 48 hrs and lysed

Human, Mouse, Rat

$523
Cat # M01983
100 µl

NR2E3 (NM_016346) Human Over-expression Lysate

NR2E3 Human Over-expression Lysates NM_014249

Human

$628
Cat # LS010002
20 µg, 100 µg

Anti-NR2E3 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # A01983-1
100 μl/vial

NR2E3 Overview

Facts about Photoreceptor-specific nuclear receptor.

NR2E3 3D structure. Source: alphafold

Photoreceptor-specific nuclear receptor (NR2E3)

Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of pole development and repressor of cone development.

Binds the promoter region of a number of pole - and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression.

Gene Information

Human
Gene Name:	NR2E3
Uniprot:	Q9Y5X4
Entrez:	10002

Family

Belongs to:

nuclear hormone receptor family

Alternative Names

NR2E3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; PNRESCS; rd7; Retina-specific nuclear receptor; RNR; RP37MGC49976

Molecular Weight

Mass (kDA):
44.692 kDA

Genomic Context


Human

Location:	15q23
Sequence:	15; NC_000015.10 (71810554..71818253)

Tissue Specificity

Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside.

Subcellular Localizations

Nucleus.

Diseases

Retinal Degeneration
Retinal Diseases
Retinitis Pigmentosa
Night Blindness
Blind Vision
Abnormal Degeneration
Goldmann-favre Syndrome (disorder)
Dystrophy
Retinal Dystrophies
Dysplasia
Color Vision Defect

Retinal Dysplasia
Retinoschisis
Macule
Nervousness
Visual Impairment
Disorder Of Eye

Pathways

Phototransduction
Localization
Cell Fate Determination
Pathogenesis
Regeneration
Axon Guidance
Cell Proliferation
Photoreceptor Cell Fate Determination
Neurogenesis
Reverse Transcription
Cell Death
Post-embryonic Development
Photoreceptor Cell Development

Photoreceptor Cell Differentiation
Photoreceptor Cell Fate Specification
Fertilization
Brain Development
Axon Regeneration
Hypersensitivity
M Phase

PTMs

Acetylation

Sumoylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NR2E3

References

PMID: 10220376 by Kobayashi M., et al. Identification of a photoreceptor cell-specific nuclear receptor.

PMID: 10611353 by Chen F., et al. Retina-specific nuclear receptor: a potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Muller glial cells.