Anti-NR2E3 Antibody

PNR/NR2E3 antibody

Boster Bio Anti-NR2E3 Antibody catalog # A01983. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A01983
Size: 100ul
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-NR2E3 Antibody

View all PNR/NR2E3 Antibodies

SKU/Catalog Number

A01983

Size

100ul

Form

Liquid

Description

Boster Bio Anti-NR2E3 Antibody catalog # A01983. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NR2E3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01983)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human PC-PLD3

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A01983 is reactive to NR2E3 in Human, Mouse

Applications

A01983 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

44.692kDa

Background of PNR/NR2E3

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 5 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Cullin 5 may form a cell surface vasopressin receptor. Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2), RBX1 and MUF1, complexes with elongin BC complex (TCEB1 and TCEB2), RXB1 and TCEB3 or SOCS1 or WSB1; elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL; elongin BC complex (TCEB1 and TCEB2), RBX1, adenovirus type 5 E1B-55kDa protein and adenovirus type 5 E4-orf6. Cullin 5 Interacts with RBX1 and RNF7.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

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Gene/Protein Information For NR2E3 (Source: Uniprot.org, NCBI)

Gene Name

NR2E3

Full Name

Photoreceptor-specific nuclear receptor

Weight

44.692kDa

Superfamily

nuclear hormone receptor family

Alternative Names

NR2E3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; PNRESCS; rd7; Retina-specific nuclear receptor; RNR; RP37MGC49976 NR2E3 ESCS, PNR, RNR, RP37, rd7 nuclear receptor subfamily 2 group E member 3 photoreceptor-specific nuclear receptor|retina-specific nuclear receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NR2E3, check out the NR2E3 Infographic

NR2E3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for NR2E3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01983-100ul

100ul

$380

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