Histone-lysine N-methyltransferase NSD3 (NSD3)

Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3.

H3'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while'Lys-27' is a mark for transcriptional repression. .