Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1)

Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is needed for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (PubMed:8621606, PubMed:10686424, PubMed:15854030).

These hydroxylysines serve as sites of attachment for carbohydrate components and are vital for the stability of the intermolecular collagen cross-links (Probable). .