PLOD2 Antibodies

AND PLOD2 ELISA kits, PLOD2 Proteins

Many biological assays use antibodies to detect PLOD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLOD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLOD2 antibodies...

We validate the specificity of these antibodies to PLOD2 by testing them on tissues known to express PLOD2 positively and negatively. Browse below to find the PLOD2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PLOD2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PLOD2 IHC Guide

PLOD2 Infographic by Boster Bio

All PLOD2 Products

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Product

Figures

Specificity

Applications

Price

Anti-PLOD2 Antibody

IHC analysis of PLOD2 using anti-PLOD2 antibody (A04601-2)

Human, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A04601-2
100 μl/vial

Anti-PLOD2 Antibody

Western blot analysis of extracts of various cell lines, using PLOD2/LH2 antibody at 1:1000 dilution

Western blot analysis of extracts of Rat uterus, using PLOD2/LH2 antibody at 1:1000 dilution

Western blot analysis of extracts of Mouse uterus, using PLOD2/LH2 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A04601
100ul

PLOD2 (NM_182943) Human Over-expression Lysate

Human

$628
Cat # LS005352
20 µg, 100 µg

PLOD2 Overview

Facts about Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.

PLOD2 3D structure. Source: alphafold

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2)

Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate components and are essential for the stability of the intermolecular collagen cross-links.

Gene Information

Human
Gene Name:	PLOD2
Uniprot:	O00469
Entrez:	5352

Family

Belongs to:

No superfamily

Alternative Names

2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2; 2-oxoglutarate 5-dioxygenase 2; LH2; Lysine Hydroxylase 2; PLOD2; procollagen-lysine; telopeptide lysyl hydroxylase; TLH

Molecular Weight

Mass (kDA):
84.686 kDA

Genomic Context


Human

Location:	3q24
Sequence:	3; NC_000003.12 (146069437..146161495, complement)

Tissue Specificity

Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta.

Subcellular Localizations

Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.

Diseases

Fibrosis
Osteogenesis Imperfecta
Connective Tissue Diseases
Muscle Contracture
Neoplasms
Fracture
Hypoxia
Diffuse Scleroderma
Malignant Neoplasms
Neoplasm Metastasis
Scleroderma
Arthrogryposis

Sclerosis
Ehlers-danlos Syndrome
Carcinoma
Scoliosis, Unspecified
Osteoporosis
Liver Carcinoma

Pathways

Pathogenesis
Osteoblast Differentiation
Response To Hypoxia
Immune Response
Axon Regeneration
Ovulation
Proestrus
Regeneration
Tissue Development
Flight
Translation
Innate Immune Response

Cell Growth
Angiogenesis
Wound Healing
Rna Processing
Luteinization
Rna Interference
Viral Replication

PTMs

Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLOD2

References

PMID: 9054364 by Valtavaara M., et al. Cloning and characterization of a novel human lysyl hydroxylase isoform highly expressed in pancreas and muscle.

PMID: 10372558 by Yeowell H.N., et al. Tissue specificity of a new splice form of the human lysyl hydroxylase 2 gene.