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- Table of Contents
PRKAR1A Antibodies
AND PRKAR1A ELISA kits, PRKAR1A Proteins
Many biological assays use antibodies to detect PRKAR1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKAR1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKAR1A antibodies...
Designing an IHC experiment for PRKAR1A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PRKAR1A IHC GuidePRKAR1A Infographic by Boster Bio
All PRKAR1A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # A00699-1
100 μg/vial
Cat # A00699-1
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00699-1
100 μl/vial
Cat # M00699-1
100 μl/vial
Human
$628
Cat # LS005573
20 µg, 100 µg
Cat # LS005573
20 µg, 100 µg
Human, Mouse, Rat
ELISA
$480
Cat # EKC1676
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1676
1 kit, containing one 96-well plate and all necessary reagents
$1062
Cat # PROTP10644
20 µg
Cat # PROTP10644
20 µg
PRKAR1A Overview
Facts about cAMP-dependent protein kinase type I-alpha regulatory subunit.
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A)
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PRKAR1A |
| Uniprot: | P10644 |
| Entrez: | 5573 |
Family
| Belongs to: |
|---|
| cAMP-dependent kinase regulatory chain family |
Alternative Names
cAMP-dependent protein kinase regulatory subunit RIalpha; cAMP-dependent protein kinase type I-alpha regulatory chain; cAMP-dependent protein kinase type I-alpha regulatory subunit; CAR; CNC; CNC1; MGC17251; PKA R1 alpha; PKA1; PKR1; PPNAD1; PRKAR1; protein kinase A type 1a regulatory subunit; protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specificextinguisher 1); Tissue-specific extinguisher 1; TSE1DKFZp779L0468
Molecular Weight
Mass (kDA):
42.982 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q24.2 |
| Sequence: | 17; NC_000017.11 (68413623..68551316) |
Tissue Specificity
Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Subcellular Localizations
Cell membrane.
Diseases
- Neoplasms
- Carney Complex
- Myxoma
- Adenoma
- Cell Transformation, Neoplastic
- Malignant Neoplasms
- Multiple Endocrine Neoplasia
- Cushing Syndrome
- Pituitary Diseases
- Endocrine Gland Neoplasms
- Hyperplasia
- Tumors Of Adrenal Cortex
- Pituitary Neoplasms
Interacting Proteins
- AICDA
- C2orf88
- GABARAPL1
- PLEKHF2
- PRKACA
- PRKAR1B
- PRKX
- RFC2
- SET
Pathways
- Pigmentation
- Cell Cycle
- Pathogenesis
- Localization
- Cell Growth
- Secretion
- Cell Proliferation
- Cell Differentiation
- Oncogenesis
- Cortisol Secretion
- Excretion
- Transport
- Translation
PTMs
- Phosphorylation
- Cleavage
- Methylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKAR1A
bosterbio.com/bosterbio-gene-info-cards/PRKAR1A
References
PMID: 3426618 by Sandberg M., et al. Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis.
PMID: 2310396 by Sandberg M., et al. The two mRNA forms for the type I alpha regulatory subunit of cAMP- dependent protein kinase from human testis are due to the use of different polyadenylation site signals.