PTGER4 Antibodies

AND PTGER4 ELISA kits, PTGER4 Proteins

Many biological assays use antibodies to detect PTGER4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGER4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGER4 antibodies...

We validate the specificity of these antibodies to PTGER4 by testing them on tissues known to express PTGER4 positively and negatively. Browse below to find the PTGER4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PTGER4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PTGER4 IHC Guide

PTGER4 Infographic by Boster Bio

All PTGER4 Products

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Specificity

Applications

Price

Anti-Prostaglandin E Receptor EP4/PTGER4 Antibody Picoband®

Western blot analysis of PTGER4 using anti-PTGER4 antibody (A02153-2)

Human, Mouse, Rat

$370
Cat # A02153-2
100 μg/vial

Anti-PTGER4 Antibody (Center)

PTGER4 Antibody (Center) western blot analysis in HL-60,K562 cell line and mouse brain lysates (35ug/lane)

Immunohistochemical analysis of paraffin-embedded H

Human, Mouse

IHC-P, WB

$299
Cat # A02153
80 µl

PTGER4 Overview

Facts about Prostaglandin E2 receptor EP4 subtype.

PTGER4 3D structure. Source: alphafold

Prostaglandin E2 receptor EP4 subtype (PTGER4)

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.

Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

Gene Information

Human
Gene Name:	PTGER4
Uniprot:	P35408
Entrez:	5734

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

EP4; EP4R; MGC126583; PGE receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E receptor 4 (subtype EP4); prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER2; PTGER4

Molecular Weight

Mass (kDA):
53.119 kDA

Genomic Context


Human

Location:	5p13.1
Sequence:	5; NC_000005.10 (40679915..40740936)

Tissue Specificity

High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Mycoplasma Pneumonia
Inflammation
Malignant Neoplasms
Neoplasms
Carcinoma
Arthritis
Rheumatoid Arthritis
Neoplasm Metastasis
Ulcer
Colitis
Inflammatory Bowel Diseases
Tissue Adhesions
Malignant Neoplasm Of Breast

Carcinogenesis
Tumor Angiogenesis
Intestinal Diseases
Mammary Neoplasms
Colorectal Cancer
Cell Invasion
Pain

Pathways

Secretion
Pathogenesis
Cell Proliferation
Localization
Bone Resorption
Cytokine Production
Angiogenesis
Cell Growth
Immune Response
Parturition
Cell Migration
Inflammatory Response
Ovulation

Luteolysis
Cell Cycle
Sensitization
Vasoconstriction
Regeneration
Transport
Osteoblast Differentiation

PTMs

Phosphorylation
Demethylation
Reduction

Methylation
Dephosphorylation
Oxidation

Ubiquitination

Research Areas

Cancer
GPCR
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGER4

References

PMID: 8163486 by Bastien L., et al. Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype.

PMID: 8250933 by An S., et al. Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2.