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RAB3A Antibodies
AND RAB3A ELISA kits, RAB3A Proteins
Many biological assays use antibodies to detect RAB3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAB3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAB3A antibodies...
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RAB3A Infographic by Boster Bio
All RAB3A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$523
Cat # M03463-1
100 µl
Cat # M03463-1
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03463-3
100 μl/vial
Cat # M03463-3
100 μl/vial
RAB3A Overview
Facts about Ras-related protein Rab-3A.
Ras-related protein Rab-3A (RAB3A)
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | RAB3A |
| Uniprot: | P20336 |
| Entrez: | 5864 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
RAB3A, member RAS oncogene family; RAS-associated protein RAB3A; ras-related protein Rab-3A
Molecular Weight
Mass (kDA):
24.984 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.11 |
| Sequence: | 19; NC_000019.10 (18196784..18204042, complement) |
Tissue Specificity
Specifically expressed in brain.
Subcellular Localizations
Cytoplasm, cytosol. Lysosome. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Lipid-anchor; Cytoplasmic side. Cycles between a vesicle-associated GTP-bound form and a cytosolic GDP-bound form.
Diseases
- Nervousness
- Pituitary Diseases
- Neoplasms
- Alzheimer's Disease
- Depressive Disorder
- Diabetes Mellitus
- Malignant Neoplasms
- Pheochromocytoma
- Neuroblastoma
- Disease Of Adrenal Medulla
- Melanoma
- Schizophrenia
Interacting Proteins
- RAB3IP
- RABIF
Pathways
- Exocytosis
- Secretion
- Transport
- Localization
- Membrane Fusion
- Synaptic Transmission
- Insulin Secretion
- Vesicle Docking
- Secretory Pathway
- Acrosome Reaction
- Endocytosis
- Vesicle Fusion
- Vesicle Transport
PTMs
- Phosphorylation
- Prenylation
- Cleavage
- Geranylgeranylation
- Methylation
- Reduction
Research Areas
- Membrane Trafficking and Chaperones
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAB3A
bosterbio.com/bosterbio-gene-info-cards/RAB3A
References
PMID: 2501306 by Zahraoui A., et al. The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.
PMID: 10574328 by Sullivan M., et al. Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND.