Ras-related protein Rap-1A (RAP1A)

Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.

Together with ITGB1BP1, modulates KRIT1 localization into microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth.