RIPK4 Antibodies

AND RIPK4 ELISA kits, RIPK4 Proteins

Many biological assays use antibodies to detect RIPK4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RIPK4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RIPK4 antibodies...

We validate the specificity of these antibodies to RIPK4 by testing them on tissues known to express RIPK4 positively and negatively. Browse below to find the RIPK4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIPK4 Infographic by Boster Bio

All RIPK4 Products

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Anti-RIPK4 Antibody

Western blot analysis of extracts of A375 cells, using RIPK4 Rabbit pAb at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human liver damage using RIPK4 antibody at dilution of 1:100

Human, Mouse

IHC, WB

$405
Cat # A07084
100ul

RIPK4 (NM_020639) Human Over-expression Lysate

Human

$960
Cat # LS054101
20 µg, 100 µg

RIPK4 Overview

Facts about Receptor-interacting serine/threonine-protein kinase 4.

RIPK4 3D structure. Source: alphafold

Receptor-interacting serine/threonine-protein kinase 4 (RIPK4)

Involved in stratified epithelial development. It's a direct transcriptional target of TP63.

Plays a role in NF-kappa-B activation. .

Gene Information

Human
Gene Name:	RIPK4
Uniprot:	P57078
Entrez:	54101

Family

Belongs to:

protein kinase superfamily

Alternative Names

ANKK2; ANKRD3MGC129993; ankyrin repeat domain 3; Ankyrin repeat domain-containing protein 3; DIKMGC129992; EC 2.7.11; EC 2.7.11.1; PKC-delta-interacting protein kinase; PKK; receptor-interacting serine/threonine-protein kinase 4; receptor-interacting serine-threonine kinase 4; RIP4; serine/threonine-protein kinase ANKRD3

Molecular Weight

Mass (kDA):
91.611 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (41739373..41767052, complement)

Subcellular Localizations

Cytoplasm. Membrane; Peripheral membrane protein.

Diseases

Skin Abnormalities
Cleft Lip
Pterygium
Cleft Palate
Neurodegenerative Disorders
Craniofacial Abnormalities
Down Syndrome
Dysplasia
Malignant Neoplasms
Lymphopenia
Congenital Abnormality
Skin Neoplasms

Malignant Neoplasm Of Skin
Schizophrenia
Contact Dermatitis
Congenital Disorders
Popliteal Pterygium Syndrome
Leukemia

Interacting Proteins

BIRC2
BIRC3
DVL2
HIF1AN
XIAP

Pathways

Keratinocyte Differentiation
Cell Proliferation
Hair Follicle Development
Cell Development
Keratinocyte Development
B Cell Proliferation
Localization

Limb Development

PTMs

Phosphorylation

Cleavage

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIPK4

References

PMID: 12446564 by Meylan E., et al. RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.

PMID: 21931591 by Bertrand M.J., et al. cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4).