CLIC6 Antibodies

AND CLIC6 ELISA kits, CLIC6 Proteins

Many biological assays use antibodies to detect CLIC6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLIC6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLIC6 antibodies...

We validate the specificity of these antibodies to CLIC6 by testing them on tissues known to express CLIC6 positively and negatively. Browse below to find the CLIC6 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLIC6 Infographic by Boster Bio

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CLIC6 Overview

Facts about Chloride intracellular channel protein 6.

CLIC6 3D structure. Source: alphafold

Chloride intracellular channel protein 6 (CLIC6)

May insert into membranes and form chloride ion channels. May play a crucial role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity).

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Gene Information

Human
Gene Name:	CLIC6
Uniprot:	Q96NY7
Entrez:	54102

Family

Belongs to:

chloride channel CLIC family

Alternative Names

chloride intracellular channel 6; parchorin

Molecular Weight

Mass (kDA):
73.012 kDA

Genomic Context


Human

Location:	21q22.12
Sequence:	21; NC_000021.9 (34668953..34718223)

Tissue Specificity

Expressed in brain, placenta, pancreas and liver.

Subcellular Localizations

Cytoplasm. Cell membrane; Single-pass membrane protein. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity).

Diseases

Down Syndrome
Carcinoma
Salivary Gland Neoplasms
Stomach Neoplasms
Hereditary Hemorrhagic Telangiectasia
Helicobacter Infections
Carcinogenesis
Ulcer
Leukemia, Myelocytic, Acute
Congenital Heart Defects
Helicobacter Pylori Infection
Idiopathic Erosive/hemorrhagic Gastritis

Malignant Neoplasms
Myeloid Leukemia
Neoplasms
Pituitary Diseases
Steroid Sulfatase Deficiency Disease
Cytogenetic Abnormality

Pathways

Secretion
Acid Secretion
Protein Phosphorylation
Transport
Methylation
Cell Division
Dna Methylation
Glycosylation

Ion Transport
Metaphase
Gastric Acid Secretion

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLIC6

References

PMID: 14597386 by Friedli M., et al. Identification of a novel member of the CLIC family, CLIC6, mapping to 21q22.12.

PMID: 12226712 by Strippoli P., et al. Segmental paralogy in the human genome: a large-scale triplication on 1p, 6p, and 21q.