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- Table of Contents
TFPI2 Antibodies
AND TFPI2 ELISA kits, TFPI2 Proteins
Many biological assays use antibodies to detect TFPI2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFPI2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFPI2 antibodies...
Designing a Western blot for TFPI2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TFPI2 Western Blot GuideTFPI2 Infographic by Boster Bio
All TFPI2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # A03697-1
100 μg/vial
Cat # A03697-1
100 μg/vial
TFPI2 Overview
Facts about Tissue factor pathway inhibitor 2.
Tissue factor pathway inhibitor 2 (TFPI2)
May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa.
Has no effect on thrombin. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TFPI2 |
| Uniprot: | P48307 |
| Entrez: | 7980 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Placental protein 5; PP5; PP5FLJ21164; REF-1; TFPI2; TFPI-2; TFPI-2REF1; tissue factor pathway inhibitor 2
Molecular Weight
Mass (kDA):
26.934 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.3 |
| Sequence: | 7; NC_000007.14 (93885396..93890753, complement) |
Tissue Specificity
Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Colorectal Cancer
- Carcinoma
- Colorectal Neoplasms
- Adenocarcinoma
- Neoplasm Metastasis
- Pancreatic Neoplasm
- Malignant Neoplasm Of Pancreas
- Adenoma
- Malignant Tumor Of Cervix
- Metastatic Malignant Neoplasm To The Lymph Node
Pathways
- Methylation
- Dna Methylation
- Dna Hypermethylation
- Cell Growth
- Cell Adhesion
- Blood Coagulation
- Gene Silencing
- Dna Hypomethylation
- Immune Response
- Demethylation
- Inflammatory Response
PTMs
- Methylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFPI2
bosterbio.com/bosterbio-gene-info-cards/TFPI2
References
PMID: 7896752 by Miyagi Y., et al. cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor-2.
PMID: 8159751 by Sprecher C.A., et al. Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor.
1 Publications of Boster TFPI2 Antibodies & ELISA Kits
- PubMed ID: 10.1371/journal.pone.0173991, The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not ...
*More publications can be found for each product on its corresponding product page