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- Table of Contents
Vitamin D3 receptor Antibodies
AND VDR ELISA kits, Vitamin D3 receptor Proteins
Many biological assays use antibodies to detect Vitamin D3 receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Vitamin D3 receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Vitamin D3 receptor antibodies...
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VDR Infographic by Boster Bio
All VDR Products
Product
Figures
Specificity
Applications
Price
Anti-Vitamin D Receptor/VDR Antibody Picoband®
3 Citations 16 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9456
100 μg/vial
Cat # PB9456
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # PA1983
100 μg/vial
Cat # PA1983
100 μg/vial
Human, Mouse, Rat
IP, WB
$370
Cat # M00210
100 μl
Cat # M00210
100 μl
Human
ELISA
$480
Cat # EKC1596
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1596
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$540
Cat # EKC2344
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2344
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # A00210-1
100 μg/vial
Cat # A00210-1
100 μg/vial
VDR Overview
Facts about Vitamin D3 receptor.
Vitamin D3 receptor (VDR)
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609).
The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609). Plays a central role in calcium homeostasis (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | VDR |
| Uniprot: | P11473 |
| Entrez: | 7421 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
NR1I1; NR1I1Nuclear receptor subfamily 1 group I member 11,25-dihydroxyvitamin D3 receptor; VDR; vitamin D1,25- dihydroxyvitamin D3 receptor; vitamin D3 receptor
Molecular Weight
Mass (kDA):
48.289 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.11 |
| Sequence: | 12; NC_000012.12 (47841537..47905022, complement) |
Subcellular Localizations
Nucleus. Cytoplasm. Localizes mainly to the nucleus (PubMed:28698609, PubMed:12145331). Localization to the nucleus is enhanced by vitamin D3.
Diseases
- Malignant Neoplasms
- Neoplasms
- Osteoporosis
- Vitamin D Deficiency
- Malignant Neoplasm Of Prostate
- Malignant Neoplasm Of Breast
- Rickets
- Mammary Neoplasms
- Diabetes Mellitus
- Prostatic Neoplasms
- Carcinoma
- Hyperparathyroidism, Secondary
Interacting Proteins
- EP300
- MED1
- MEOX2
- NCOA1
- Ncoa6
- PTPN3
- RXRA
- Rxra
- SNW1
- SQSTM1
Pathways
- Cell Proliferation
- Pathogenesis
- Secretion
- Cell Differentiation
- Cell Growth
- Transport
- Cell Cycle
- Localization
- Immune Response
- Excretion
- Bone Resorption
- Aging
- Translation
PTMs
- Phosphorylation
- Acetylation
- Hydroxylation
- Methylation
- Cleavage
- Deacetylation
- Dephosphorylation
- Demethylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VDR
bosterbio.com/bosterbio-gene-info-cards/VDR
References
PMID: 2835767 by Baker A.R., et al. Cloning and expression of full-length cDNA encoding human vitamin D receptor.
PMID: 1324736 by Goto H., et al. A single receptor identical with that from intestine/T47D cells mediates the action of 1,25-dihydroxyvitamin D-3 in HL-60 cells.
2 Publications of Boster Vitamin D3 receptor Antibodies & ELISA Kits
- PubMed ID: 29218094, (+)-Cholesten-3-one induces osteogenic differentiation of bone marrow mesenchyma...
- PubMed ID: 26959817, Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Ha...
*More publications can be found for each product on its corresponding product page