Anti-ABRA1 Purified ABRAXAS1 Monoclonal Antibody

Abraxas antibody

Boster Bio Anti-ABRA1 Purified ABRAXAS1 Monoclonal Antibody (Catalog# M32338). Tested in Flow Cytometry, IP, WB application(s). This antibody reacts with Human.

Product Info Summary

SKU: M32338
Size: 0.1 mg
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IP, WB

Product Name

Anti-ABRA1 Purified ABRAXAS1 Monoclonal Antibody

View all Abraxas Antibodies

SKU/Catalog Number

M32338

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ABRA1 Purified ABRAXAS1 Monoclonal Antibody (Catalog# M32338). Tested in Flow Cytometry, IP, WB application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-ABRA1 Purified ABRAXAS1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M32338)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

ABRA1-01

Isotype

Mouse IgG2a kappa

Immunogen

Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag. The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M32338 is reactive to Abraxas1 in Human

Applications

M32338 is guaranteed for Flow Cytometry, IP, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

46.039kDa

Background of Abraxas

ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-2 μg/ml. Intracellular staining.
Western blotting: Reducing conditions.

Validation Images & Assay Conditions

Gene/Protein Information For Abraxas1 (Source: Uniprot.org, NCBI)

Gene Name

Abraxas1

Full Name

BRCA1-A complex subunit Abraxas 1

Weight

46.039kDa

Superfamily

FAM175 family

Alternative Names

BRCA1-A complex subunit Abraxas; ABRA1; CCDC98; family with sequence similarity 175, member A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Abraxas1, check out the Abraxas1 Infographic

Abraxas1 infographic

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In this infographic, you will see the following information for Abraxas1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Total: $326

SKU:M32338

Backordered.

Lead time for this item is typically 10-14 days

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Eddy test
In stock
Order Product
M32338
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$326.00

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