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We validate the specificity of these antibodies to Abraxas1 by testing them on tissues known to express Abraxas1 positively and negatively. Browse below to find the Abraxas1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.
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Facts about BRCA1-A complex subunit Abraxas 1.
The BRCA1-A complex specifically recognizes'Lys-63'-connected ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes'Lys-63'-linked ubiquitin on histones H2A and H2AX.
BRCA1-A complex subunit Abraxas; ABRA1; CCDC98; family with sequence similarity 175, member A