|Ig Isotype||Mouse IgG1|
|Product Name||Anti-Beta-HCG Antibody (Monoclonal, PC-2)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for beta-HCG, chorionic gonadotropin, beta polypeptide (CGB) detection. Tested with IHC-P in Human. Cross-reactivities with LH, FSH and TSH are less than 0.3%.|
|Cite This Product||Anti-Beta-HCG Antibody (Monoclonal, PC-2) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1111)|
|Contents/Buffer||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Immunogen||Purified human Chorionic Gonadotropin.|
Assay Dilutions Overview
Immunohistochemistry(Paraffin-embedded Section), 2μg/ml, Human, By Heat
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
Images And Assay Conditions
Anti-beta-HCG antibody (monoclonal), MA1111, IHC(P)
IHC(P): Human Placenta Tissue
Protein Target Info (Source: Uniprot.org)
|Protein Name||Choriogonadotropin subunit beta|
|Alternative Names||Choriogonadotropin subunit beta;CG-beta;Chorionic gonadotrophin chain beta;CGB;CGB3;CGB5;CGB7;CGB8;|
|Molecular Weight||17739 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.|
|Research Areas||Chromatin Remodeling, Co-Factors, Epigenetics And Nuclear Signaling, Transcription
*You can search these to find other products in these research areas.
|Background||beta-HCG(beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain(CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.|
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