Anti-c-Fms (E557) CSF1R Antibody

M-CSFR/CD115 antibody

Boster Bio Anti-c-Fms (E557) CSF1R Antibody catalog # A00082. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A00082
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC

Product Name

Anti-c-Fms (E557) CSF1R Antibody

View all M-CSFR/CD115 Antibodies

SKU/Catalog Number

A00082

Size

100ul

Form

Liquid

Description

Boster Bio Anti-c-Fms (E557) CSF1R Antibody catalog # A00082. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-c-Fms (E557) CSF1R Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00082)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CSF1R, which shares 96.8% amino acid (aa) sequence identity with both mouse and rat CSF1R.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00082 is reactive to CSF1R in Human, Mouse, Rat

Applications

A00082 is guaranteed for IF, IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

107.984kDa

Background of M-CSFR/CD115

Beta amyloid, often abbreviated as A-beta, is a protein that builds up in the brains of persons with Alzheimer's disease, collecting in clumps called plaques or senile plaques. While some researchers question whether beta amyloid is the cause of the dementia, most agree that it is involved in the disruption of thinking that is a hallmark of the disease. In some cases of familial Alzheimer's disease, mutations in genes for the proteins called the presenilins lead to increased production of amyloid. Researchers have been looking at how presenilin-1 in particular contributes to the excess buildup of beta amyloid. Presenilin-1 apparently acts to increase the activity of gamma-secretase, an enzyme that changes a normal protein (amyloid precursor protein or APP) into beta amyloid itself. Furthermore, presenilin-1 might be gamma-secretase. Anti-Beta Amyloid Antibody is useful for researchers interested in TLR signaling and Alzheimer's research.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 1:50-1:200
IF: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For CSF1R (Source: Uniprot.org, NCBI)

Gene Name

CSF1R

Full Name

Macrophage colony-stimulating factor 1 receptor

Weight

107.984kDa

Superfamily

protein kinase superfamily

Alternative Names

CD115 antigen; CD115; c-fms; colony stimulating factor 1 receptor; CSF1R; CSF-1-R; CSFR; EC 2.7.10.1; FMS proto-oncogene; FMSFIM2; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSF R; MCSFR; M-CSFR; Proto-oncogene c-Fms CSF1R BANDDOS, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R colony stimulating factor 1 receptor macrophage colony-stimulating factor 1 receptor|CD115 antigen|CSF-1 receptor|FMS proto-oncogene|McDonough feline sarcoma viral (v-fms) oncogene homolog|macrophage colony stimulating factor I receptor|proto-oncogene c-Fms

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CSF1R, check out the CSF1R Infographic

CSF1R infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CSF1R: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00082-100ul

100ul

$405

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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