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SKU BA1054
Pack size 0.5 ml
Applications Western blot

Product Overview

Product Name Goat Anti-Rabbit IgG (H+L) Secondary Antibody, HRP Conjugate
Synonyms HRP-conjugated goat anti-rabbit IgG
Description Goat Anti-Rabbit IgG (H+L) Secondary Antibody, HRP Conjugate, for the indirect sensitive immunodetection and/or quantification of target proteins through Dot Blot, WB, or ELISA by assaying an HRP-catalyzed reaction product in the vicinity of the antigen-primary antibody-secondary antibody-HRP complex.
Reagent Type Secondary antibody, reporter enzyme labeled
Label HRP (Horseradish Peroxidase)
Host Goat
Target Species Rabbit
Antibody Class IgG
Clonality Polyclonal
Immunogen Whole molecule rabbit IgG
Purification Immunoaffinity Chromatography
Specificity Rabbit IgG specific; No cross-reactivity with related species
Form Supplied Liquid: concentrated buffered stock solution
Formulation 0.5 mg HRP-conjugated secondary antibody
0.01 M PBS (PH 7.4)
50% glycerol
Pack Size 0.5 ml
Concentration 1 mg/ml
Application ELISA*, WB*, Dot blot
*Our Boster Guarantee covers the use of this product in the above marked tested applications.
Storage 4C for 1 year
Precautions FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR CLINICAL USE

Assay Information

Sample Type SDS-PAGE separated-, membrane-immobilized-, mouse primary-antibody-probed proteins from cell/tissue lysates
Assay Type Immunoassay
Assay Purpose Protein detection/quantification
Technique Immunodetection of target antibody with HRP reporter enzyme
Equipment Needed WB/Dot blot/ELISA instrumentation; X-ray film cassette or a charge-coupled device (CCD) imager; Spectrophotometer
Compatibility with Reagents Incompatible with sodium azide and metals
incompatible with high phosphate concentrations

Main Advantages

Specific High signal-to-noise ratio
Sensitive Detects low-abundant targets due to an optimal number of HRP molecules per antibody
High Signal Amplification Multiple secondary antibodies can bind to a single primary antibody;Secondary antibodies Fc regions provide further binding locations for biotin, or enable the use of ABC and SABC
Fast Generates strong signals in a relatively short time span
Quantifieable Allows quantification of detected signal
Easy to Use Supplied in a workable liquid format
Flexible HRP: compatible with chromogenic, fluorogenic and chemiluminescent substrates;
Convenient HRP’s small size: no interference with the primary/secondary antibody interaction; no steric hindrance to antibody/antigen complexes

Background

Most commonly, secondary antibodies are generated by immunizing the host animal with a pooled population of immunoglobulins from the target species. The host antiserum is then purified through immunoaffinity chromatography to remove all host serum proteins, except the specific antibody of interest, and are then modified with antibody fragmentation, label conjugation, etc. Secondary antibodies can be conjugated to a large number of labels, including enzymes, biotin, and fluorescent dyes/proteins. Here, the antibody provides the specificity to locate the protein of interest, and the label generates a detectable signal. The label of choice depends upon the experimental application.

Horseradish peroxidase (HRP) is extensively used for labeling secondary antibodies in ELISA, western blot, dot blot and immunohistochemistry. The HRP enzyme is made visible using a substrate that, when oxidized by HRP in the presence of hydrogen peroxide as an oxidizing agent, yields a characteristic change that is detectable by specific detection methods. The substrates commonly used with HRP fall into different categories including chromogenic, fluorogenic, and chemiluminescent substrates depending on whether they produce a colored, fluorimetric or luminescent derivative respectively. The intensity of the signal is proportional to peroxidase activity and is a measure of the number of enzyme molecules reacting, hence of the amount of recognized primary antibodies, and thus of the amount of target antigen.

Goat Anti-Rabbit IgG (H+L) Secondary Antibody, HRP Conjugate Images

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Goat Anti-Rabbit IgG (H+L) Secondary Antibody, HRP Conjugate
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Publications

Magnesium isoglycyrrhizinate has hepatoprotective effects in an oxaliplatin%u2011induced model of liver injury
Benfotiamine, a Lipid-Soluble Analog of Vitamin B1, Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) %u2026
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/%u03B2-catenin signaling pathway
Regulation of matriptase and HAI-1 system, a novel therapeutic target in human endometrial cancer cells
Low-intensity pulsed ultrasound in combination with SonoVue induces cytotoxicity of human renal glomerular endothelial cells via repression of the ERK1/2 signaling %u2026
MicroRNA-150 inhibits the proliferation and metastasis potential of colorectal cancer cells by targeting iASPP
Overexpression of Tau Rescues Nogo-66-Induced Neurite Outgrowth Inhibition In Vitro
Monoacylglycerol lipase inhibitor JZL184 regulates apoptosis and migration of colorectal cancer cells
Role of peroxiredoxin 2 in H2O2%u2011induced oxidative stress of primary Leydig cells
TRPM8 downregulation by angiotensin II in vascular smooth muscle cells is involved in hypertension
Treatment of type 2 diabetes mellitus via reversing insulin resistance and regulating lipid homeostasis in vitro and in vivo using cajanonic acid A
miR%u2011186 promotes tumor growth in cutaneous squamous cell carcinoma by inhibiting apoptotic protease activating factor%u20111
microRNA%u201122 attenuates myocardial ischemia%u2011reperfusion injury via an anti%u2011inflammatory mechanism in rats
Cortical spreading depression preconditioning mediates neuroprotection against ischemic stroke by inducing AMP%u2010activated protein kinase%u2010dependent autophagy in %u2026
C5a aggravates dysfunction of the articular cartilage and synovial fluid in rats with knee joint immobilization
Estrogen receptor-related receptor %u03B1 mediates up-regulation of aromatase expression by prostaglandin E2 in prostate stromal cells
Over-expressed and truncated midkines promote proliferation of BGC823 cells in vitro and tumor growth in vivo
Proliferation and differentiation of rat adipose%u2011derived stem cells are regulated by yes%u2011associated protein
TGF%u03B21-Smad Signaling Pathway Participates in Interleukin-33 Induced Epithelial-to-Mesenchymal Transition of A549 Cells
Glucagon-like peptide 1 receptor agonist ameliorates the insulin resistance function of islet %u03B2 cells via the activation of PDX-1/JAK signaling transduction in %u2026
Hypoxia promotes maintenance of the chondrogenic phenotype in rat growth plate chondrocytes through the HIF-1%u03B1/YAP signaling pathway
Retinal and choroidal expression of BMP-2 in lens-induced myopia and recovery from myopia in guinea pigs
Ginsenoside Rg1 exerts a protective effect against A%u03B225-35-induced toxicity in primary cultured rat cortical neurons through the NF-%u03BAB/NO pathway
Sequencing and Expression Characterization of Antifreeze Protein Maxi-Like in Apis cerana cerana
Mechanism Investigation of the Improvement of Chang Run Tong on the Colonic Remodeling in Streptozotocin-Induced Diabetic Rats
Role of p19ink4d in the pathogenesis of hearing loss
Targeting Pin1 Protects Mouse Cardiomyocytes from High-Dose Alcohol-Induced Apoptosis
AAL exacerbates pro-inflammatory response in macrophages by regulating Mincle/Syk/Card9 signaling along with the Nlrp3 inflammasome assembly
Low expression of KLF17 is associated with tumor invasion in esophageal carcinoma
Hepatitis C virus non-structural 5A abrogates signal transducer and activator of transcription-1 nuclear translocation induced by IFN-alpha through dephosphorylation.
Knockdown of FOXA2 enhances the osteogenic differentiation of bone marrow-derived mesenchymal stem cells partly via activation of the ERK signalling pathway
Transcriptomic differential lncRNA expression is involved in neuropathic pain in rat dorsal root ganglion after spared sciatic nerve injury
Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma
Effects of Pinocembrin Pretreatment on Connexin 43 (Cx43) Protein Expression After Rat Myocardial Ischemia-Reperfusion and Cardiac Arrhythmia
Polyphenol Stilbenes from Fenugreek (Trigonella foenum-graecum L.) Seeds Improve Insulin Sensitivity and Mitochondrial Function in 3T3-L1 Adipocytes
Injectable OPF/graphene oxide hydrogels provide mechanical support and enhance cell electrical signaling after implantation into myocardial infarct
Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson?s Disease Mouse Model
Interaction of S100A1 with LATS1 promotes cell growth through regulation of the Hippo pathway in hepatocellular carcinoma
Exogenous glutathione contributes to cisplatin resistance in lung cancer A549 cells
Effect of Qiangji Jianli decoction on mitochondrial respiratory chain activity and expression of mitochondrial fusion and fission proteins in myasthenia gravis rats
Acetylation-Dependent Regulation of Notch Signaling in Macrophages by SIRT1 Affects Sepsis Development
Elongation Factor Thermo Unstable (EF-Tu) Moonlights as an Adhesin on the Surface of Mycoplasma hyopneumoniae by Binding to Fibronectin
Tiaolipiwei Acupuncture Reduces Albuminuria by Alleviating Podocyte Lesions in a Rat Model of Diabetic Nephropathy
Dioscin suppresses the viability of ovarian cancer cells by regulating the VEGFR2 and PI3K/AKT/MAPK signaling pathways
Asiatic acid prevents the development of interstitial lung disease in a hypochlorous acid-induced mouse model of scleroderma
Protective effect and mechanism of Lactobacillus on cerebral ischemia reperfusion injury in rats
Peptidoglycan Suppresses Phagocytic Activities and Apoptosis of Macrophages in Colonic Mucosa Tissues of Crohn?s Disease Patients and In Vitro
Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca2+ and activating the FAK/Rho GTPases signaling pathways in vitro
Dynamic expression and roles of sequestome-1/p62 in LPS-induced acute kidney injury in mice
Effects of Yangzheng Sanjie Decoction-containing serum mediated by microRNA-7 on cell proliferation and apoptosis in gastric cancer
Comparative study of macrophages in naked mole rats and ICR mice
Inhibition of penile tunica albuginea myofibroblasts activity by adipose-derived stem cells
MicroRNA-212 inhibits the proliferation, migration and invasion of renal cell carcinoma by targeting X-linked inhibitor of apoptosis protein (XIAP)
Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells
Molecular diagnosis of citrin deficiency in an infant with intrahepatic cholestasis: identification of a 21.7kb gross deletion that completely silences the transcriptional and translational expression of the affected SLC25A13 allele
An optimized HMGB1 expressed by recombinant rabies virus enhances immunogenicity through activation of dendritic cells in mice
Luteolin inhibits multi-heavy metal mixture-induced HL7702 cell apoptosis through downregulation of ROS-activated mitochondrial pathway
miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages
WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects
High expression of Sam68 in sacral chordomas is associated with worse clinical outcomes
Role of caspase-3/E-cadherin in helicobacter pylori-induced apoptosis of gastric epithelial cells
LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells
iTRAQ-Based Quantitative Proteomics Analysis of the Protective Effect of Yinchenwuling Powder on Hyperlipidemic Rats
Identification of a novel envelope protein encoded by ORF 136 from Cyprinid herpesvirus 3
Nova1 mediates resistance of rat pheochromocytoma cells to hypoxia-induced apoptosis via the Bax/Bcl-2/caspase-3 pathway
Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPK?-regulated autophagy induction in streptozotocin-induced diabetic nephropathy
Inhibitory effect of quercetin on titanium particle induced endoplasmic reticulum stress related apoptosis and in vivo osteolysis
Hypertonic saline infusion suppresses apoptosis of hippocampal cells in a rat model of cardiopulmonary resuscitation
Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy
Exo70 is an independent prognostic factor in colon cancer
The influence of connective tissue growth factor on rabbit ligament injury repair
Resveratrol protects against L-arginine-induced acute necrotizing pancreatitis in mice by enhancing SIRT1-mediated deacetylation of p53 and heat shock factor 1
Escape of U251 glioma cells from temozolomide-induced senescence was modulated by CDK1/survivin signaling
High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2
RNA-binding protein HuR promotes bladder cancer progression by competitively binding to the long noncoding HOTAIR with miR-1
Inhibition of cell proliferation, migration and apoptosis in blue-light illuminated human retinal pigment epithelium cells by down-regulation of HtrA1
Notch signaling is important for epithelial-mesenchymal transition induced by low concentrations of doxorubicin in osteosarcoma cell lines
Pentamethylquercetin induces adipose browning and exerts beneficial effects in 3T3-L1 adipocytes and high-fat diet-fed mice
Recipient Glycemic Micro-environments Govern Therapeutic Effects of Mesenchymal Stem Cell Infusion on Osteopenia
Resveratrol protects against early polymicrobial sepsis-induced acute kidney injury through inhibiting endoplasmic reticulum stress-activated NF-?B pathway
Insufficient hypothalamic angiotensin-converting enzyme 2 is associated with hypertension in SHR rats
Caveolin-1 scaffolding domain peptides enhance anti-inflammatory effect of heme oxygenase-1 through interrupting its interact with caveolin-1
Antioxidant axis Nrf2-keap1-ARE in inhibition of alcoholic liver fibrosis by IL-22
Integrin ?1 Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction
Hypoxia regulates CD44 expression via hypoxia-inducible factor-1? in human gastric cancer cells
Myosin IIA-related Actomyosin Contractility Mediates Oxidative Stress-induced Neuronal Apoptosis
Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway
Hypoxia-Inducible Factor-1? Promotes Endometrial Stromal Cells Migration and Invasion by Upregulating Autophagy in Endometriosis
Helicteric Acid, Oleanic Acid, and Betulinic Acid, Three Triterpenes from Helicteres angustifolia L., Inhibit Proliferation and Induce Apoptosis in HT-29 Colorectal Cancer Cells via Suppressing NF-?B and STAT3 Signaling
Silencing nc886, a Non-Coding RNA, Induces Apoptosis of Human Endometrial Cancer Cells-1A In Vitro
Tumor Cell-Derived Microvesicles Induced Not Epithelial-Mesenchymal Transition but Apoptosis in Human Proximal Tubular (HK-2) Cells: Implications for Renal Impairment in Multiple Myeloma
RNAi for contactin 2 inhibits proliferation of U87-glioma stem cells by downregulating AICD, EGFR, and HES1
pH-sensitive micelles for the intracellular co-delivery of curcumin and Pluronic L61 unimers for synergistic reversal effect of multidrug resistance
Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-?B
Ginsenoside Rg1 improves fertility and reduces ovarian pathological damages in premature ovarian failure model of mice
Anti-Tumor Effects of Atractylenolide-I on Human Ovarian Cancer Cells
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-?B Signaling Pathway
N-n-butyl Haloperidol Iodide Protects against Hypoxia/Reoxygenation Injury in Cardiac Microvascular Endothelial Cells by Regulating the ROS/MAPK/Egr-1 Pathway
Tunneling nanotubes promote intercellular mitochondria transfer followed by increased invasiveness in bladder cancer cells
MicroRNA-297a regulates vascular calcification by targeting fibroblast growth factor 23
Fermented Chinese Formula Shuan-Tong-Ling Protects Brain Microvascular Endothelial Cells against Oxidative Stress Injury
Impact of perinatal exposure to acetaminophen on hepatocellular metabolic function in offspring
Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca2+-ATPase 2 Expression in Diabetic Nephropathy
Long-Term Alteration of Reactive Oxygen Species Led to Multidrug Resistance in MCF-7 Cells
Corilagin ameliorates the extreme inflammatory status in sepsis through TLR4 signaling pathways
Inhibition of histone acetylation by curcumin reduces alcohol-induced fetal cardiac apoptosis
miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1
Pallidin protein in neurodevelopment and its relation to the pathogenesis of schizophrenia
Effect of dexmedetomidine on hippocampal neuron development and BDNF-TrkB signal expression in neonatal rats
Microcystin-Leucine Arginine Causes Cytotoxic Effects in Sertoli Cells Resulting in Reproductive Dysfunction in Male Mice
Aptamer-PEG-modified Fe3O4@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells
Down-regulation of microRNA-451a facilitates the activation and proliferation of CD4+ T cells by targeting Myc in patients with dilated cardiomyopathy
NEMO-Binding Domain Peptide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting the NF-?B Signaling Pathway
Clinicopathological Features and Prognosis of Papillary Thyroid Microcarcinoma for Surgery and Relationships with the BRAFV600E Mutational Status and Expression of Angiogenic Factors
Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like phenotype via the TGF-?1/Smad3 pathway
Upregulating miR-146a by physcion reverses multidrug resistance in human chronic myelogenous leukemia K562/ADM cells
Osthole protects sepsis-induced acute kidney injury via down-regulating NF-?B signal pathway
RNAi-mediated gene silencing of vascular endothelial growth factor C suppresses growth and induces apoptosis in mouse breast cancer?in vitro?and?in vivo
PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth
microRNA-22 attenuates myocardial ischemia-reperfusion injury via an anti-inflammatory mechanism in rats
Ginsenoside Rg1 Protects against Oxidative Stress-induced Neuronal Apoptosis through Myosin IIA-actin Related Cytoskeletal Reorganization
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway
Therapeutic role of human hepatocyte growth factor (HGF) in treating hair loss
IGF-1/IGF-1R/hsa-let-7c axis regulates the committed differentiation of stem cells from apical papilla
Improvement of Electroacupuncture on APP/PS1 Transgenic Mice in Spatial Learning and Memory Probably due to Expression of A? and LRP1 in Hippocampus
Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse
Mesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice
Transplantation of autologous bone marrow mononuclear cells regulates inflammation in a rabbit model of carotid artery atherosclerosis
miR-139-5p regulates proliferation, apoptosis, and cell cycle of uterine leiomyoma cells by targeting TPD52
Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimulating glial cell line-derived neurotrophic factor (GDNF) production in Sertoli cells
Monoacylglycerol Lipase: A Novel Potential Therapeutic Target and Prognostic Indicator for Hepatocellular Carcinoma
Acupuncture Alters Expression of Insulin Signaling Related Molecules and Improves Insulin Resistance in OLETF Rats
PD-L1 is upregulated by EBV-driven LMP1 through NF-?B pathway and correlates with poor prognosis in natural killer/T-cell lymphoma
Effects of Huang Qi Decoction on Endothelial Dysfunction Induced by Homocysteine
MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)
Autophagy Is Associated with Pathogenesis of?Haemophilus parasuis
TFP5 prevents 1-methyl-4-phenyl pyridine ion-induced neurotoxicity in mouse cortical neurons
C1 inhibitor-mediated myocardial protection from chronic intermittent hypoxia-induced injury
Physcion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinoma
Ocular Albinism Type 1 Regulates Melanogenesis in Mouse Melanocytes
TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A
Effect of Thyrotropin on Osteopontin, Integrin ?v?3,?and VCAM-1 in the Endothelium via Activation of Akt
Effects and mechanisms of docosahexaenoic acid on the generation of angiopoietin-2 by rat brain microvascular endothelial cells under an oxygen- and glucose-deprivation environment
Heat shock protein 70 protects PC12?cells?against ischemia-hypoxia/reoxygenation by maintaining intracellular Ca(2+) homeostasis
HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway
miR-541 Contributes to Microcystin-LR-Induced Reproductive Toxicity through Regulating the Expression of p15 in Mice
A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal?cell?apoptosis
Development of a Sandwich ELISA for EHEC O157:H7 Intimin ?1
Comparative proteomic analysis of extracellular matrix proteins secreted by hypertrophic scar with normal skin fibroblasts
Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells
Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1
Allicin protects traumatic spinal cord injury through regulating the HSP70/Akt/iNOS pathway in mice
Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion
Mouse Maternal High-Fat Intake Dynamically Programmed mRNA m?A Modifications in Adipose and Skeletal Muscle Tissues in Offspring
Imbalance between Glutamate and GABA in Fmr1 Knockout Astrocytes Influences Neuronal Development
CCL21/CCR7 Axis Contributed to CD133+ Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-?B Pathway
Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway
The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration
MicroRNA-145 Mediates Steroid-Induced Necrosis of the Femoral Head by Targeting the OPG/RANK/RANKL Signaling Pathway
miR-877-3p targets Smad7 and is associated with myofibroblast differentiation and bleomycin-induced lung fibrosis
Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension
Downregulation of HP1? suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression
A single amino acid substitution in a chitinase of the legume Medicago truncatula is sufficient to gain Nod-factor hydrolase activity
Investigation of JAKs/STAT?3 in lipopolysaccharide?induced intestinal epithelial cells
MicroRNA-21a-5p Functions on the Regulation of Melanogenesis by Targeting Sox5 in Mouse Skin Melanocytes
Rhubarb attenuates blood-brain barrier disruption via increased zonula occludens-1 expression in a rat model of intracerebral hemorrhage
miR-494 inhibits ovarian cancer cell proliferation and promotes apoptosis by targeting FGFR2
Alpha-1 Antitrypsin Prevents the Development of Preeclampsia Through Suppression of Oxidative Stress
miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor
Preventive Effects of Rhodiola rosea L on Bleomycin-Induced Pulmonary Fibrosis in Rats
Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury
GCN5 modulates osteogenic differentiation of periodontal ligament stem cells through DKK1 acetylation in inflammatory microenvironment
Metformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson's Disease via Autophagy and Mitochondrial ROS Clearance
The Effect of Minimally Invasive Hematoma Aspiration on the JNK Signal Transduction Pathway after Experimental Intracerebral Hemorrhage in Rats
Penehyclidine ameliorates acute lung injury by inhibiting Toll-like receptor 2/4 expression and nuclear factor-?B activation
Cloning and Characterization of Sf9 Cell Lamin and the Lamin Conformational Changes during Autographa californica multiple nucleopolyhedrovirus Infection
Effects of p53 on aldosterone-induced mesangial cell apoptosis in vivo and in vitro
Central antinociceptive activity of peripherally applied botulinum toxin type A in lab rat model of trigeminal neuralgia
Protection Efficacy of the Extract of Ginkgo biloba against the Learning and Memory Damage of Rats under Repeated High Sustained +Gz Exposure
Quantitative Proteomic Analysis of Duck Ovarian Follicles Infected with Duck Tembusu Virus by Label-Free LC-MS
Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer
The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H pylori
Endogenous TWEAK is critical for regulating the function of mouse uterine natural killer cells in an immunological model of pregnancy loss
Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-?B signal pathway
SIRT3 Deficiency Induces Endothelial Insulin Resistance and Blunts Endothelial-Dependent Vasorelaxation in Mice and Human with Obesity
Spinal Glutamate Transporters Are Involved in the Development of Electroacupuncture Tolerance
Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors
MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11
miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway
Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection
Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis
Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars
Roles of mycobacterium tuberculosis ESAT-6 in the development of renal injury
Effect of bone marrow mesenchymal stem cells transplantation on the serum and liver HMGB1 expression in rats with acute liver failure
Inhibition of acute lung injury by rubriflordilactone in LPS-induced rat model through suppression of inflammatory factor expression
miR-342-5p Is a Notch Downstream Molecule and Regulates Multiple Angiogenic Pathways Including Notch, Vascular Endothelial Growth Factor and Transforming Growth Factor ? Signaling
Thioredoxin 1 protects astrocytes from oxidative stress by maintaining peroxiredoxin activity
ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy
Cyclic AMP responsive element-binding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochore-associated protein 2
MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1
Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone
Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide
Characterization of a Secretory Annexin in Echinococcus granulosus
Development and application of an indirect enzyme-linked immunosorbent assay using recombinant truncated Cap protein for the diagnosis of porcine circovirus-like virus P1
DNA Demethylation Upregulated Nrf2 Expression in Alzheimer's Disease Cellular Model
Argirein alleviates stress-induced and diabetic hypogonadism in rats via normalizing testis endothelin receptor A and connexin 43
miR-525-5p inhibits ADAMTS13 and is correlated with Ischemia/reperfusion injury-induced neuronal cell death
Cysteine Dioxygenase Type 1 Inhibits Osteogenesis by Regulating Wnt Signaling in Primary Mouse Bone Marrow Stromal Cells
Phosphatidylinositol 3-Kinase Promotes Activation and Vacuolar Acidification and Delays Methyl Jasmonate-Induced Leaf Senescence
Effect of activation of the Ca2+-permeable acid-sensing ion channel 1a on focal cerebral ischemia in diabetic rats
Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway.
The Expression of Porcine Prdx6 Gene Is Up-Regulated by C/EBP? and CREB
TGF-?2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway
Traditional Chinese medicine Qili qiangxin inhibits cardiomyocyte apoptosis in rats following myocardial infarction
Shikonin Inhibits Inflammatory Response in Rheumatoid Arthritis Synovial Fibroblasts via lncRNA-NR024118
microRNA-20a enhances the epithelial-to-mesenchymal transition of colorectal cancer cells by modulating matrix metalloproteinases
Expression of Robo protein in bladder cancer tissues and its effect on the growth of cancer cells by blocking Robo protein
The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia
FK506 reduces albuminuria through improving podocyte nephrin and podocin expression in diabetic rats
Genes associated with sodium fluoride-induced human osteoblast apoptosis.
Aging increases the susceptibility of cisplatin-induced nephrotoxicity
Stem cell protein Piwil1 endowed endometrial cancer cells with stem-like properties via inducing epithelial-mesenchymal transition
Overexpression of mitochondrial Hsp75 protects neural stem cells against microglia-derived soluble factor-induced neurotoxicity by regulating mitochondrial permeability transition pore opening?in vitro
The SUMO Protease SENP3 Orchestrates G2-M Transition and Spindle Assembly in Mouse Oocytes
Microencapsulation improves inhibitory effects of transplanted olfactory ensheathing cells on pain after sciatic nerve injury
Effect of angiotensin-(1-7) and angiotensin II on the proliferation and activation of human endometrial stromal cells in vitro
Experimental study of the protective effects of SYVN1 against diabetic retinopathy
Knockdown of Gli1 by small-interfering RNA enhances the effects of BCNU on the proliferation and apoptosis of glioma U251 cells
Alteration of ASIC1 expression in clear cell renal cell carcinoma
Curcumin combined with FAP?c vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-? in melanoma
Epigenetic silencing of olfactomedin-4 enhances gastric cancer cell invasion via activation of focal adhesion kinase signaling
Annexin A5 regulates Leydig cell testosterone production via ERK1/2 pathway
Zuogui Jiangtang Jieyu Formulation Prevents Hyperglycaemia and Depressive-Like Behaviour in Rats by Reducing the Glucocorticoid Level in Plasma and Hippocampus
BAMBI Promotes C2C12 Myogenic Differentiation by Enhancing Wnt/?-Catenin Signaling
Electromagnetic radiation at 900?MHz induces sperm apoptosis through bcl-2, bax and caspase-3 signaling pathways in rats
Autologous bone marrow mononuclear cell transplantation delays progression of carotid atherosclerosis in rabbits
RLN2 Is a Positive Regulator of AKT-2-Induced Gene Expression Required for Osteosarcoma Cells Invasion and Chemoresistance
Effect of valsartan on ACAT-1 and PPAR-? expression in intima with carotid artery endothelial balloon injury in rabbit
The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144
RNAi-mediated knockdown of?INHBB?increases apoptosis and inhibits steroidogenesis in mouse granulosa cells
Effects of dexamethasone on aquaporin-4 expression in brain tissue of rat with bacterial meningitis
The 656C and 725C are two important sites in gene?STGC3?for its negative regulation on cell growth
SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling
Effects of electroacupuncture on recovery of the electrophysiological properties of the rabbit gastrocnemius after contusion: an in vivo animal study
Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats
Fructus phyllanthi tannin fraction induces apoptosis and inhibits migration and invasion of human lung squamous carcinoma cells in vitro via MAPK/MMP pathways
Andrographolide suppresses proliferation of nasopharyngeal carcinoma cells via attenuating NF-?B pathway.
Increased expression of receptor for advanced glycation end-products worsens focal brain ischemia in diabetic rats
?-lipoic acid protects against hypoxia/reoxygenation-induced injury in human umbilical vein endothelial cells through suppression of apoptosis and autophagy
Adenovirus-mediated transfection with glucose transporter 3 suppresses PC12 cell apoptosis following ischemic injury
Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation
The influence of astragalus polysaccharide and ?-elemene on LX-2 cell growth, apoptosis and activation
HSF1 functions as a transcription regulator for Dp71 expression
Licochalcone A up-regulates of FasL in mesenchymal stem cells to strengthen bone formation and increase bone mass
Toll-like receptor 4 implicated in acute lung injury induced by paraquat poisoning in mice
17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway
Glimepiride Promotes Osteogenic Differentiation in Rat Osteoblasts via the PI3K/Akt/eNOS Pathway in a High Glucose Microenvironment
Ginsenoside Rb1 Prevents H2O2-Induced HUVEC Senescence by Stimulating Sirtuin-1 Pathway
Overexpression of Rcan1-1L Inhibits Hypoxia-Induced Cell Apoptosis through Induction of Mitophagy
Evaluating the Role of PTH in Promotion of Chondrosarcoma Cell Proliferation and Invasion by Inhibiting Primary Cilia Expression
Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygenase-2 inhibitor
Single Prolonged Stress induces ATF6 alpha-dependent Endoplasmic reticulum stress and the apoptotic process in medial Frontal Cortex neurons
Stanniocalcin 2 expression predicts poor prognosis of hepatocellular carcinoma
Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells
IL-17 regulates the expressions of RANKL and OPG in human periodontal ligament cells via TRAF6/TBK1-JNK/NF-?B pathways.
Expression and function of Delta-like ligand 4 in a rat model of retinopathy of prematurity
PD-L1 is increased in the spinal cord and infiltrating lymphocytes in experimental allergic encephalomyelitis
ClC-3 chloride channel in hippocampal neuronal apoptosis
Chloride channel blocker 4,4-diisothiocyanatostilbene-2,2?-disulfonic acid inhibits nitric oxide-induced apoptosis in cultured rat hippocampal neurons
Changes of hypoxia-inducible factor-1 signaling and the effect of cilostazol in chronic cerebral ischemia
Radix Achyranthis Bidentatae improves learning and memory capabilities in ovariectomized rats
Effect of minocycline on cerebral ischemia-reperfusion injury
Effect of Vitamin E Supplementation on Intestinal Barrier Function in Rats Exposed to High Altitude Hypoxia Environment
Zinc Supplementation Protects against Cadmium Accumulation and Cytotoxicity in Madin-Darby Bovine Kidney Cells
Roles of TLR3 and RIG-I in Mediating the Inflammatory Response in Mouse Microglia following Japanese Encephalitis Virus Infection
Oxygen-Carbon Nanotubes as a Chemotherapy Sensitizer for Paclitaxel in Breast Cancer Treatment
Apelin-13 Decreases Lipid Storage in Hypertrophic Adipocytes?In Vitro?Through the Upregulation of AQP7 Expression by the PI3K Signaling Pathway
Swainsonine Induces Apoptosis through Mitochondrial Pathway and Caspase Activation in Goat Trophoblasts
Guanxinkang Decoction Exerts Its Antiatherosclerotic Effect Partly through Inhibiting the Endoplasmic Reticulum Stress
FHL1C induces apoptosis in notch1-dependent T-ALL cells through an interaction with RBP-J
Urantide improves atherosclerosis by controlling C-reactive protein, monocyte chemotactic protein-1 and transforming growth factor-? expression in rats
Lipopolysaccharide differentially affects the osteogenic differentiation of periodontal ligament stem cells and bone marrow mesenchymal stem cells through Toll-like receptor 4 mediated nuclear factor ?B pathway
Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization
Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/?-Catenin Signaling Pathway
Periodontal Ligament Stem Cells Modulate Root Resorption of Human Primary Teeth via Runx2 Regulating RANKL/OPG System
Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment
The?Streptococcus suis?transcriptional landscape reveals adaptation mechanisms in pig blood and cerebrospinal fluid
The Low Chamber Pancreatic Cancer Cells Had Stem-Like Characteristics in Modified Transwell System: Is It a Novel Method to Identify and Enrich Cancer Stem-Like Cells?
Immunization with H7-HCP-Tir-Intimin Significantly Reduces Colonization and Shedding of?Escherichia coli?O157:H7 in Goats
Comparative study of the immunogenicity in mice and monkeys of an inactivated CA16 vaccine made from a human diploid cell line
Function of the transforming growth factor-?1/c-Jun N-terminal kinase signaling pathway in the action of thalidomide on a rat model of pulmonary fibrosis
ERK/CANP rapid signaling mediates 17?-estradiol-induced proliferation of human breast cancer cell line MCF-7 cells
Protective Effect of Wheat Peptides against Indomethacin-Induced Oxidative Stress in IEC-6 Cells
N-n-Butyl Haloperidol Iodide Ameliorates Cardiomyocytes Hypoxia/Reoxygenation Injury by Extracellular Calcium-Dependent and -Independent Mechanisms
Dickkopf-1 Is Oncogenic and Involved in Invasive Growth in Non Small Cell Lung Cancer
Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells
LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn?s disease
Inhibition of choriocarcinoma by Fe3O4-dextran-anti-?-human chorionic gonadotropin nanoparticles containing antisense oligodeoxynucleotide of heparanase
Hypoxia/oxidative stress alters the pharmacokinetics of CPU86017-RS through mitochondrial dysfunction and NADPH oxidase activation
Heat Shock Protein 70 Is Associated with Replicase Complex of Japanese Encephalitis Virus and Positively Regulates Viral Genome Replication
Electrospun Poly(L-lactide)/Poly(?-caprolactone) Blend Nanofibrous Scaffold: Characterization and Biocompatibility with Human Adipose-Derived Stem Cells
The Time Course Effects of Electroacupuncture on Promoting Skeletal Muscle Regeneration and Inhibiting Excessive Fibrosis after Contusion in Rabbits
Estrogen deficiency reduces the dentinogenic capacity of rat lower incisors
Cyclic Tensile Stress During Physiological Occlusal Force Enhances Osteogenic Differentiation of Human Periodontal Ligament Cells via ERK1/2-Elk1 MAPK Pathway
Development of porcine rotavirus vp6 protein based ELISA for differentiation of this virus and other viruses
The expression and distribution of aquaporin 3 in mouse embryos before and after vitrification
AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration
Serum GP73, a Marker for Evaluating Progression in Patients with Chronic HBV Infections
Transient overexpression of TGFBR3 induces apoptosis in human nasopharyngeal carcinoma CNE-2Z cells
Caveolin-1 Regulates Rac1 Activation and Rat Pulmonary Microvascular Endothelial Hyperpermeability Induced by TNF-?
Cellular Mechanism Underlying Formaldehyde-Stimulated Cl??Secretion in Rat Airway Epithelium
A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection against influenza A virus and?Staphylococcus aureus
Pro-survival effect of Dock180 overexpression on rat-derived H9C2 cardiomyocytes
Excessive Astrocyte-Derived Neurotrophin-3 Contributes to the Abnormal Neuronal Dendritic Development in a Mouse Model of Fragile X Syndrome
Elevated expression of C3G protein in the peri-infarct myocardium of rats
Cloning of the Quail PIWI Gene and Characterization of PIWI Binding to Small RNAs
Antibody Fragments Directed against Different Portions of the Human Neural Cell Adhesion Molecule L1 Act as Inhibitors or Activators of L1 Function
Molecular Adjuvant Ag85A Enhances Protection against Influenza A Virus in Mice Following DNA Vaccination
Temporal and Spatial Regulation of Ezrin-Radixin-Moesin-Binding Phosphoprotein-50-kDa (EBP50) during Embryo Implantation in Mouse Uterus
Adenoviral 15-lipoxygenase-1 gene transfer inhibits hypoxia-induced proliferation of retinal microvascular endothelial cells in vitro
In vitro and in vivo studies of surface-structured implants for bone formation
Special AT-rich sequence binding protein 1 regulates the multidrug resistance and invasion of human gastric cancer cells
Down-Regulation of GEP100 Causes Increase in E-Cadherin Levels and Inhibits Pancreatic Cancer Cell Invasion
Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells
Expression of neuroglobin in ocular hypertension induced acute hypoxic-ischemic retinal injury in rats
The Extra Domain A of Fibronectin Increases VEGF-C Expression in Colorectal Carcinoma Involving the PI3K/AKT Signaling Pathway
CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines
Serine 129 Phosphorylation of??-Synuclein Cross-Links with Tissue Transglutaminase to Form Lewy Body-Like Inclusion Bodies
Pre-Absorbed Immunoproteomics: A Novel Method for the Detection of
Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis
Ultrastructure and melatonin 1a receptor distribution in the ovaries of African ostrich chicks
Estrogen Receptor-Related Receptor ? Mediates Up-Regulation of Aromatase Expression by Prostaglandin E2 in Prostate Stromal Cells
Identification of 20-Hydroxyecdysone Late-Response Genes in the Chitin Biosynthesis Pathway
Lowered HGK expression inhibits cell invasion and adhesion in hepatocellular carcinoma cell line HepG2
Acute Stress and Chronic Stress Change Brain-Derived Neurotrophic Factor (BDNF) and Tyrosine Kinase-Coupled Receptor (TrkB) Expression in Both Young and Aged Rat Hippocampus
Nucleolin/C23 is a negative regulator of hydrogen peroxide-induced apoptosis in HUVECs
Different Functions of the Insect Soluble and Membrane-Bound Trehalase Genes in Chitin Biosynthesis Revealed by RNA Interference
Investigating the Role of P311 in the Hypertrophic Scar
Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes
Detection of B. anthracis Spores and Vegetative Cells with the Same Monoclonal Antibodies
Emodin protects rat liver from CCl4-induced fibrogenesis via inhibition of hepatic stellate cells activation
LFA-1 and CD2 Synergize for the Erk1/2 Activation in the Natural Killer (NK) Cell Immunological Synapse
Over-expressed and truncated midkines promote proliferation of BGC823 cells
Upregulation of the constitutively expressed HSC70 by KLF4
Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes
Expression of Mipu1 in Response to Myocardial Infarction in Rats
Maternal Transfer and Protective Role of the Alternative Complement Components in Zebrafish Danio rerio
Y4lO of Rhizobium sp. Strain NGR234 Is a Symbiotic Determinant Required for Symbiosome Differentiation
Symbiosis-Promoting and Deleterious Effects of NopT, a Novel Type 3 Effector of Rhizobium sp. Strain NGR234
Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor ?-Independent Pathway
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Customer Q&As

Q: What species have been tested for the cross-reactivity of BA1054 Goat Anti-Rabbit IgG (H+L) Secondary Antibody, HRP Conjugate ?
A: Mouse and Bovine has been tested. It showed no cross-reactivity with mouse/bovine IgG.
Q: Is this product suitable for IHC? Keyword: application, Immunohistochemistry
A: Please beware that this product is not suitable for IHC. Small package of secondaries (0.5 ml) can do 15-75 slides and 1ml can do 30-150 slides. The difference is in the way customer uses the reagent.