Product Info Summary
SKU: | A02157 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-DUSP6 (L76) Antibody
View all MKP-3/DUSP6 Antibodies
SKU/Catalog Number
A02157
Size
100ul
Form
Liquid
Description
Boster Bio Anti-DUSP6 (L76) Antibody catalog # A02157. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DUSP6 (L76) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02157)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from N-terminal of human SENP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02157 is reactive to DUSP6 in Human, Mouse, Rat
Applications
A02157 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
42.32kDa
Background of MKP-3/DUSP6
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity.
Taihei Yamaguchi, Mol. Cell. Biol., Jun 2005; 25: 5171 - 5182.
Jinke Cheng, Mol. Cell. Biol., Jul 2004; 24: 6021 - 6028.
Molly A. Brewer, AACR Meeting Abstracts, Mar 2004; 2004: 1006.
Imke M. Veltman, Hum. Mol. Genet., Jul 2005; 14: 1955 - 1963.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of DUSP6 using Anti-DUSP6 (L76) Antibody (A02157).
Immunohistochemistry (IHC) analyzes of DUSP6 (L76) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For DUSP6 (Source: Uniprot.org, NCBI)
Gene Name
DUSP6
Full Name
Dual specificity protein phosphatase 6
Weight
42.32kDa
Superfamily
protein-tyrosine phosphatase family
Alternative Names
dual specificity phosphatase 6; Dual specificity protein phosphatase PYST1; DUSP6; EC 3.1.3.16; EC 3.1.3.48; MAP kinase phosphatase 3; Mitogen-activated protein kinase phosphatase 3; MKP3; MKP-3; MKP3serine/threonine specific protein phosphatase; PYST1; PYST1dual specificity protein phosphatase 6 DUSP6 HH19, MKP3, PYST1 dual specificity phosphatase 6 dual specificity protein phosphatase 6|MAP kinase phosphatase 3|dual specificity protein phosphatase PYST1|mitogen-activated protein kinase phosphatase 3|serine/threonine specific protein phosphatase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DUSP6, check out the DUSP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DUSP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DUSP6 (L76) Antibody (A02157)
Hello CJ!
No publications found for A02157
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