|Validated Species:||Human, Rabbit|
Data & Images
|Product Name||Anti-Gelsolin Antibody (Monoclonal, GS-2C4)|
|Description||Mouse IgG monoclonal antibody for Gelsolin, gelsolin (GSN) detection. Tested with WB, IHC-P, IHC-F in Human; rabbit. No cross reactivity with other proteins.|
|Cite This Product||Anti-Gelsolin Antibody (Monoclonal, GS-2C4) GS-2C4 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1044)|
|Replacement Item||This antibody may replace the following items: sc-22600|sc-22602|sc-271001|sc-398244|sc-48769|sc-514502|sc-57509|sc-6405|sc-6406 from Santa Cruz Biotechnology.|
|Validated Species||Human, Rabbit|
*Our Boster Guarantee covers the use of this product in the above tested applications.
**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.
|Recommended Detection Systems||Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2018!
|Immunogen||Human plasma gelsolin.|
|Cross Reactivity||No cross reactivity with other proteins|
|Contents||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Concentration||Add 1ml of PBS buffer will yield a concentration of 100ug/ml.|
|Storage||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
Protein Target Info (Source: Uniprot.org)
You can check the tissue specificity below for information on selecting positive and negative control.
|Molecular Weight||86068 MW|
|Protein Function||Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). .|
|Tissue Specificity||GSN: Phagocytic cells, platelets, fibroblasts,nonmuscle cells, smooth and skeletal muscle cells.|
|Sequence Similarities||Belongs to the villin/gelsolin family.|
|Subcellular Localization||Isoform 1: Secreted .|
|Alternative Names||Gelsolin;Actin-depolymerizing factor;ADF;Brevin;Gsn;|
|Research Areas|||signal transduction|cytoskeleton / ecm|cytoskeleton|microfilaments|actin etc|actin binding proteins||
Background for Gelsolin
Anti-Gelsolin Antibody (Monoclonal, GS-2C4) Images
Click the images to enlarge.
IHC(P): Human Lung Cancer Tissue
IHC(P): Human Intestinal Cancer Tissue