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- Table of Contents
Gelsolin Antibodies
AND GSN ELISA kits, Gelsolin Proteins
Many biological assays use antibodies to detect Gelsolin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gelsolin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gelsolin antibodies...
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GSN Infographic by Boster Bio
All GSN Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA2109
100 μg/vial
Cat # PA2109
100 μg/vial
Anti-Gelsolin/GSN Antibody Picoband®
1 Citations
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9209
100 μg/vial
Cat # PB9209
100 μg/vial
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01598
100 μl
Cat # M01598
100 μl
GSN Overview
Facts about Gelsolin.
Gelsolin (GSN)
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed.
Plays a role in ciliogenesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GSN |
| Uniprot: | P06396 |
| Entrez: | 2934 |
Family
| Belongs to: |
|---|
| villin/gelsolin family |
Alternative Names
Actin-depolymerizing factor; ADF; AGEL; Brevin; DKFZp313L0718; gelsolin (amyloidosis, Finnish type); Gelsolin; GSN
Molecular Weight
Mass (kDA):
85.698 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q33.2 |
| Sequence: | 9; NC_000009.12 (121201483..121332844) |
Tissue Specificity
Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.
Subcellular Localizations
[Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 1]: Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Pain
- Amyloidosis
- Dystrophy
- Amyloidosis, Familial
- Carcinoma
- Hereditary Corneal Dystrophy
- Carcinoma, Transitional Cell
- Visceral Pain
- Bladder Neoplasm
Interacting Proteins
- AR
- ARRB1
- ARRB2
Pathways
- Pathogenesis
- Localization
- Cell Death
- Transport
- Cell Cycle
- Cell Adhesion
- Cell Activation
- T Cell Activation
- Aging
- Neurogenesis
- Cardiac Conduction
- Inflammatory Response
- Flight
PTMs
- Phosphorylation
Research Areas
- Apoptosis
- Cancer
- Cell Biology
- Cellular Markers
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GSN
bosterbio.com/bosterbio-gene-info-cards/GSN
References
PMID: 3020431 by Kwiatkowski D.J., et al. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.
PMID: 6092370 by Lind S.E., et al. Human plasma gelsolin binds to fibronectin.
3 Publications of Boster Gelsolin Antibodies & ELISA Kits
- PubMed ID: 10.1002/2211-5463.12997, Cystatin C regulates the cytotoxicity of infection‐induced endothelial‐deriv...
- PubMed ID: 33030263, Balczon R, Morrow KA, Leavesley S, Francis CM, Stevens TC, Agwaramgbo E, William...
- PubMed ID: 28656274, Guo, Y., Cui, L., Jiang, S., Zhang, A., & Jiang, S. (2017). Proteomics of acute ...
*More publications can be found for each product on its corresponding product page