Anti-GLP1/GCG Antibody Picoband™

GCG antibody

Boster Bio Anti-GLP1/GCG Antibody Picoband™ catalog # PB9705. Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat. Cited in 9 publication(s).

Product Info Summary

SKU: PB9705
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC

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Product Name

Anti-GLP1/GCG Antibody Picoband™

View all GCG Antibodies

SKU/Catalog Number

PB9705

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-GLP1/GCG Antibody Picoband™ catalog # PB9705. Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GLP1/GCG Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9705)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human GLP1, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9705 is reactive to GCG in Human, Mouse, Rat

Applications

PB9705 is guaranteed for IF, IHC Boster Guarantee

Observed Molecular Weight

10 kDa

Calculated molecular weight

20.909kDa

Background of GCG

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue. It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Immunofluorescence, 2μg/ml, Rat

Validation Images & Assay Conditions

Gene/Protein Information For GCG (Source: Uniprot.org, NCBI)

Gene Name

GCG

Full Name

Glucagon

Weight

20.909kDa

Superfamily

glucagon family

Alternative Names

GCG; glicentin-related polypeptide; GLP1; GLP-1; Glucagon; glucagon-like peptide 1; glucagon-like peptide 2; GRPP GCG GLP-1, GLP1, GLP2, GRPP glucagon pro-glucagon|glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2|preproglucagon

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GCG, check out the GCG Infographic

GCG infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GCG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9705 has been cited in 9 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Huo K,Li X,Hu W,Song X,Zhang D,Zhang X,Chen X,Yuan J,Zuo J,Wang X.RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose Homeostasis.Front Endocrinol (Lausanne). 2020 Apr 9;11:194.doi:10.3389/fendo.2020.00194.PMID
Species: Rat
PB9705 usage in article: APP:IHC, SAMPLE:PANCREATIC TISSUE, DILUTION:1:100

The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus

Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System

Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil?lymphocyte ratio in rats with or without hidden diabetes mellitus

Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice

Chen Ll, Yang Wh, Zheng J, Hu X, Kong W, Zhang Hh. Nutr Metab (Lond). 2010 May 26;7:45. Doi: 10.1186/1743-7075-7-45. Effect Of Catch-Up Growth After Food Restriction On The Entero-Insular Axis In Rats.

Lan F, Yue X, Han L, Shi Z, Yang Y, Pu P, Yao Z, Kang C. Int J Oncol. 2012 Feb;40(2):519-26. Doi: 10.3892/Ijo.2011.1215. Epub 2011 Sep 28. Genome-Wide Identification Of Tcf7L2/Tcf4 Target Mirnas Reveals A Role For Mir-21 In Wnt-Driven Epithelial C...

Zhang Y, Ye C, Wang G, Gao Y, Tan K, Zhuo Z, Liu Z, Xia H, Yang D, Li P. Biomed Res Int. 2013;2013:526367. Doi: 10.1155/2013/526367. Epub 2013 May 27. Kidney-Targeted Transplantation Of Mesenchymal Stem Cells By Ultrasound-Targeted Microbubble Des...

Tang Mm, Zhu Qe, Fan Wz, Zhang Sl, Li Dz, Liu Lz, Chen M, Zhang M, Zhou J, Wei Cj. Mol Ther. 2011 Jan;19(1):60-6. Doi: 10.1038/Mt.2010.187. Epub 2010 Sep 14. Intra-Arterial Targeted Islet-Specific Expression Of Sirt1 Protects ?? Cells From Strepto...

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1 Customer Q&As for Anti-GLP1/GCG Antibody Picoband™

Question

We are currently using anti-GLP1/GCG antibody PB9705 for mouse tissue, and we are happy with the IHC-P results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on canine tissues as well?

Verified Customer

Verified customer

Asked: 2018-08-06

Answer

The anti-GLP1/GCG antibody (PB9705) has not been tested for cross reactivity specifically with canine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-08-06

Order DetailsPrice
PB9705

100μg

$370
PB9705-10ug

10μg sample (liquid)

$99
PB9705-Biotin

100 μg Biotin conjugated

$570
PB9705-Cy3

100 μg Cy3 conjugated

$570
PB9705-Dylight488

100 μg Dylight488 conjugated

$570
PB9705-Dylight550

100 μg Dylight550 conjugated

$570
PB9705-Dylight594

100 μg Dylight594 conjugated

$570
PB9705-FITC

100 μg FITC conjugated

$570
PB9705-HRP

100 μg HRP conjugated

$570
PB9705-APC

100 μg APC conjugated

$670
PB9705-PE

100 μg PE conjugated

$670
PB9705-carrier-free

Carrier Free

$370

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