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Product Info Summary
|Reactive Species:||Human, Mouse, Rabbit, Rat|
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Anti-Glucagon Gcg Antibody (Monoclonal, K79bB10)
Boster Bio Anti-Glucagon Gcg Antibody (Monoclonal, K79bB10) catalog # MA1047. Tested in IHC applications. This antibody reacts with Human, Mouse, Rabbit, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Glucagon Gcg Antibody (Monoclonal, K79bB10) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1047)
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Polymerized porcine glucagon.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross-reactivity with other proteins
MA1047 is reactive to Gcg in Human, Mouse, Rabbit, Rat
MA1047 is guaranteed for IHC Boster Guarantee
Background of Gcg
Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. The human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human, mouse, rat, rabbit, By Heat
Validation Images & Assay Conditions
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Anti-Glucagon antibody (monoclonal), MA1047, IHC(P)
IHC(P): Rat Pancreas Tissue
Gene/Protein Information For Gcg (Source: Uniprot.org, NCBI)
GCG; glicentin-related polypeptide; GLP1; GLP-1; Glucagon; glucagon-like peptide 1; glucagon-like peptide 2; GRPP Gcg|GLP-1, Glp1|glucagon|pro-glucagon|glucagon-like peptide-1*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on Gcg, check out the Gcg Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Gcg: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
MA1047 has been cited in 10 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Huo K,Li X,Hu W,Song X,Zhang D,Zhang X,Chen X,Yuan J,Zuo J,Wang X.RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose Homeostasis.Front Endocrinol (Lausanne). 2020 Apr 9;11:194.doi:10.3389/fendo.2020.00194.PMID
MA1047 usage in article: APP:IHC, SAMPLE:PANCREATIC TISSUE, DILUTION:1:100
The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus
Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System
Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil?lymphocyte ratio in rats with or without hidden diabetes mellitus
Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice
Chen Ll, Yang Wh, Zheng J, Hu X, Kong W, Zhang Hh. Nutr Metab (Lond). 2010 May 26;7:45. Doi: 10.1186/1743-7075-7-45. Effect Of Catch-Up Growth After Food Restriction On The Entero-Insular Axis In Rats.
Lan F, Yue X, Han L, Shi Z, Yang Y, Pu P, Yao Z, Kang C. Int J Oncol. 2012 Feb;40(2):519-26. Doi: 10.3892/Ijo.2011.1215. Epub 2011 Sep 28. Genome-Wide Identification Of Tcf7L2/Tcf4 Target Mirnas Reveals A Role For Mir-21 In Wnt-Driven Epithelial C...
Jiang H, Deng Xf, Duan Cm, Chen C, Xiang Jl, Lu Yl, Ma Qf. Lymphology. 2011 Mar;44(1):21-8. Somatostatin Receptors Sstr2 And Sstr5 Are Expressed In The Human Thoracic Duct.
Zhang Y, Ye C, Wang G, Gao Y, Tan K, Zhuo Z, Liu Z, Xia H, Yang D, Li P. Biomed Res Int. 2013;2013:526367. Doi: 10.1155/2013/526367. Epub 2013 May 27. Kidney-Targeted Transplantation Of Mesenchymal Stem Cells By Ultrasound-Targeted Microbubble Des...
Zhang W, Jin H, Hu Y, Yu Y, Li X, Ding Z, Kang Y, Wang B. Hum Gene Ther. 2010 Feb;21(2):171-8. Doi: 10.1089/Hum.2009.095. Protective Response Against Type 1 Diabetes In Nonobese Diabetic Mice After Coimmunization With Insulin And Dna Encoding Proi...
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