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- Table of Contents
MFN2 antibody (A00461) performs well in ELISA, IF, IHC-P, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 1 Publication
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Immunofluorescence of MFN2 in rat brain tissue with MFN2 antibody at 20 μg/mL.
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Anti-Mitofusin-2 MFN2 Antibody
MFN2 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, IF, IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
MFN2 antibody can be used for detection of MFN2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Mitofusin-2 MFN2 Antibody
View all MFN2 Antibodies
View all MFN2 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
MFN2 antibody can be stored at 4°C, stable for up to one year.
Host
Rabbit
Contents
MFN2 antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MFN2 antibody was raised against a 17 amino acid peptide near the center of human MFN2. The immunogen is located within amino acids 250 - 300 of MFN2.
Cross-Reactivity
MFN2 antibody is human, mouse and rat reactive. At least three isoforms of MFN2 are known to exist. MFN2 antibody is predicted to not cross-react with MFN1.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
86.4 kDa
Background of MFN2
Mitofusin 2 (MFN2) and the related protein MFN1 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN2 is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. MFN2 has two key domains: a coiled coil region that mediates MFN2 binding and a GTPase domain that likely plays a role in fusion (3,4). Both domains are essential for embryonic development and may play a role in the pathobiology of obesity. Overexpression of MFN2 causes mitochondrial dysfunction and cell death (5).
Cite This Product
Anti-Mitofusin-2 MFN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00461)
Publications
Application:
Species:
Jiao Z,Wu Y,Qu S.Fenpropathrin induces degeneration of dopaminergic neurons via disruption of the mitochondrial quality control system.Cell Death Discov.2020 Aug 25;6:78.doi:10.1038/s41420-020-00313-y.PMID:32884840;PMCID:PMC7447795.
Species: Mouse
PMID: 32884840
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Product Promise
We promise Anti-Mitofusin-2 MFN2 Antibody performs excellently in relevant applications for ELISA, IF, IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
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A00461
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 12, 2026